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诃子鞣酸

诃子鞣酸用途

Chebulagic acid是一个从果实中提取出来的COX-LOX双重抑制剂。有抗炎和抗感染的效果。

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诃子鞣酸名称

[ CAS 号 ]:
23094-71-5

[ 中文名 ]:
诃子鞣质

[ 英文名 ]:
Chebulagic acid

[中文别名 ]:

诃子鞣酸

[英文别名 ]:

Chebulagic acid
CHEBULAGIC ACID(RG)

诃子鞣酸生物活性

[ 描述 ]:

Chebulagic acid是一个从果实中提取出来的COX-LOX双重抑制剂。有抗炎和抗感染的效果。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

天然产物 >> 酚类

[参考文献]

[1]. Kim HJ et al. Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells. Biomol Ther (Seoul). 2014 Jul;22(4):275-81.

[2]. Liu Y et al. Chebulagic acid inhibits the LPS-induced expression of TNF-α and IL-1β in endothelial cells by suppressing MAPK activation. Exp Ther Med. 2015 Jul;10(1):263-268.

[3]. Athira AP et al. Inhibition of Angiogenesis In Vitro by Chebulagic Acid: A COX-LOX Dual Inhibitor. Int J Vasc Med. 2013;2013:843897.

[相关活性小分子]

诃子鞣酸物理化学性质

[ 密度 ]:
2.1±0.1 g/cm3

[ 沸点 ]:
1610.6±65.0 °C at 760 mmHg

[ 熔点 ]:
>300℃

[ 分子式 ]:
C₄₁H₃₀O₂₇

[ 分子量 ]:
954.661

[ 闪点 ]:
480.0±27.8 °C

[ 精确质量 ]:
954.097473

[ PSA ]:
447.09000

[ LogP ]:
2.25

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.876

[ 储存条件 ]:
-20°C

诃子鞣酸安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

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诃子鞣酸文献

Chemical changes during fermentation of Abhayarishta and its standardization by HPLC-DAD.

Nat. Prod. Commun. 5(4) , 575-9, (2010)

Abhayarishta is an Ayurvedic formulation prepared traditionally by the fermentation of the decoction of Terminalia chebula (pericarp), Vitis vinifera (fruits), Embelia ribes (fruits) and Madhuca indic...

[Analysis of tannins in Fructus Chebulae and its confusion varieties by HPCE].

Yao Xue Xue Bao 36(4) , 292-5, (2001)

To analyze the hydrolyzable tannins-chebulinic acid (I) and chebulagic acid(II) in Fructus Chebulae and its confusion varieties by using high performance capillary electrophoresis (HPCE) method.Using ...

[Assay of three hydrolyzable tannins in Fructus Chebulae from different habitats by RP-HPLC].

Zhong Yao Cai 23(6) , 328-30, (2000)

Three hydrolyzable tannins chebulinic acid (I), chebulagic acid(II) and 1,3, 6-tri-O-galloyl-beta-D-glucose (III) in Fructus Chebulae from different habitats were determined by RP-HPLC method. The con...

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