Antiviral agent 20

更新时间：2025-09-11 16:29:57

Antiviral agent 20用途

抗病毒药物20(化合物17b)是一种选择性的抗寨卡病毒感染抑制剂,EC50为4.5µM。抗病毒药物20具有低细胞毒性[1]。

英文名	Antiviral agent 20

描述	抗病毒药物20(化合物17b)是一种选择性的抗寨卡病毒感染抑制剂,EC50为4.5µM。抗病毒药物20具有低细胞毒性[1]。
相关类别	信号通路 >> 抗感染 >> 流感病毒研究领域 >> 感染
靶点实验	EC50: 4.5 µM (Zika virus)
参考文献	[1]. Li F, et al. Design, synthesis and discovery of andrographolide derivatives against Zika virus infection. Eur J Med Chem. 2020 Feb 1;187:111925.

分子式	C₃₁H₃₅Cl₂NO₆
分子量	588.52

实验名称：Cytotoxicity against african green monkey Vero cells incubated for 48 hrs
来源：ChEMBL
靶标：Vero
External Id：CHEMBL5241439

实验名称：Cytotoxicity against human SNB-19 cells incubated for 24 hrs
来源：ChEMBL
靶标：SNB-19
External Id：CHEMBL5241438

实验名称：Antiviral activity against Zika virus PRVABC-59 infected in human SNB19 cells assesse...
来源：ChEMBL
靶标：Zika virus
External Id：CHEMBL4604145

实验名称：Selectivity index, ratio of CC50 for cytotoxicity against african green monkey Vero c...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5241441

实验名称：Selectivity index, ratio of CC50 for cytotoxicity against human SNB-19 cells to EC50 ...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5241440

实验名称：Selectivity index, ratio of CC50 for human SNB19 cells to EC50 for Zika virus PRVABC-...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4604147

实验名称：Cytotoxicity against human SNB19 cells assessed as reduction in cell viability incuba...
来源：ChEMBL
靶标：SNB-19
External Id：CHEMBL4604146

实验名称：Selectivity index, ratio of CC50 for African green monkey Vero cells to EC50 for Zika...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4604149

实验名称：Antiviral activity against ZIKV PRVABC59
来源：ChEMBL
靶标：Zika virus
External Id：CHEMBL5241437

实验名称：Cytotoxicity against African green monkey Vero cells assessed as reduction in cell vi...
来源：ChEMBL
靶标：Vero
External Id：CHEMBL4604148

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