Antitubercular agent-21

• 常用名: Antitubercular agent-21
• 英文名: Antitubercular agent-21
• CAS号: 2412142-93-7
• 分子量: 334.44
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₅H₂₂N₆OS
• 熔点: N/A
• 闪点: N/A

Antitubercular agent-21用途

抗结核药物-21(化合物15)是一种抗结核药物,对结核分枝杆菌H37Rv的MIC为0.4µg/mL。抗结核药物-21对革兰氏阳性、革兰氏阴性或真菌等其他微生物的活性较低。抗结核药物-21的细胞毒性较低[1]。

Antitubercular agent-21名称

• 英文名: Antitubercular agent-21

Antitubercular agent-21生物活性

• 描述: 抗结核药物-21(化合物15)是一种抗结核药物,对结核分枝杆菌H37Rv的MIC为0.4µg/mL。抗结核药物-21对革兰氏阳性、革兰氏阴性或真菌等其他微生物的活性较低。抗结核药物-21的细胞毒性较低[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Krause M, et al. 4-Substituted picolinohydrazonamides as a new class of potential antitubercular agents. Eur J Med Chem. 2020 Mar 15;190:112106.

Antitubercular agent-21物理化学性质

• 分子式: C₁₅H₂₂N₆OS
• 分子量: 334.44

Antitubercular agent-21靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse B16-F10 cells assessed as necrotic cells at 5 ug/ml by mic... 来源：ChEMBL 靶标：B16-F10 External Id：CHEMBL4768128

实验名称：Cytotoxicity against human NHDF cells assessed as effect on morphological changes at ... 来源：ChEMBL 靶标：NHDF External Id：CHEMBL4768129

实验名称：Antifungal activity against Candida parapsilosis ATCC 22019 assessed as reduction in ... 来源：ChEMBL 靶标：Candida parapsilosis External Id：CHEMBL4768122

实验名称：Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability incu... 来源：ChEMBL 靶标：B16-F10 External Id：CHEMBL4768123

实验名称：Antifungal activity against Candida albicans ATCC 102231 assessed as reduction in fun... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4768120

实验名称：Antifungal activity against Candida albicans ATCC 2091 assessed as reduction in funga... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4768121

实验名称：Selectivity index, ratio of IC50 for cytotoxicity against human NHDF cells to MIC for... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4768126

实验名称：Cytotoxicity against mouse B16-F10 cells assessed as effect on morphological changes ... 来源：ChEMBL 靶标：B16-F10 External Id：CHEMBL4768127

实验名称：Cytotoxicity against human NHDF cells assessed as reduction in cell viability incubat... 来源：ChEMBL 靶标：NHDF External Id：CHEMBL4768124

实验名称：Selectivity index, ratio of IC50 for cytotoxicity against human NHDF cells to IC50 fo... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4768125

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