Tabimorelin hemifumarate

• 常用名: Tabimorelin hemifumarate
• 英文名: Tabimorelin hemifumarate
• CAS号: 242143-80-2
• 分子量: 586.72
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₂H₄₀N₄O_3.1/₂C₄H₄O₄
• 熔点: N/A
• 闪点: N/A

Tabimorelin hemifumarate用途

Tabimorelin(NN703)半富马酸盐是一种口服活性生长激素(GH)促分泌剂。半富马酸Tabimorelin也是CYP3A4活性的有效抑制剂[1]。

Tabimorelin hemifumarate名称

• 英文名: Tabimorelin hemifumarate

Tabimorelin hemifumarate生物活性

• 描述: Tabimorelin(NN703)半富马酸盐是一种口服活性生长激素(GH)促分泌剂。半富马酸Tabimorelin也是CYP3A4活性的有效抑制剂[1]。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> 代谢酶/蛋白酶 >> 细胞色素P450
• 靶点实验:

  CYP3A4

• 参考文献:

  [1]. Zdravkovic M, et al. A clinical study investigating the pharmacokinetic interaction between NN703 (tabimorelin), a potential inhibitor of CYP3A4 activity, and midazolam, a CYP3A4 substrate. Eur J Clin Pharmacol. 2003 Feb;58(10):683-8.

Tabimorelin hemifumarate物理化学性质

• 分子式: C₃₂H₄₀N₄O_3.1/₂C₄H₄O₄
• 分子量: 586.72
• 精确质量: 1172.630981
• InChIKey: YQDJPWXYLLPOPW-LWTUVRFUSA-N
• SMILES: CNC(=O)C(Cc1ccccc1)N(C)C(=O)C(Cc1ccc2ccccc2c1)N(C)C(=O)C=CCC(C)(C)N.CNC(=O)C(Cc1ccccc1)N(C)C(=O)C(Cc1ccc2ccccc2c1)N(C)C(=O)C=CCC(C)(C)N.O=C(O)C=CC(=O)O

Tabimorelin hemifumarate靶点实验

查看更多实验

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Enzymatic assay of human HDAC6 with custom peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808150

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4513082

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303805

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Tocris HTS for Inhibitors of Aerobactin Synthetase lucA 来源：23265 External Id：IucA Pilot Assay Tocris Library

共8条，当前第1页，共1页

1

Tabimorelin hemifumarate英文别名

• D-Phenylalaninamide, N-[(2E)-5-amino-5-methyl-1-oxo-2-hexen-1-yl]-N-methyl-3-(2-naphthalenyl)-D-alanyl-N,Nα-dimethyl-, (2E)-2-butenedioate (2:1)
• N-[(2E)-5-Amino-5-methyl-2-hexenoyl]-N-methyl-3-(2-naphthyl)-D-alanyl-N,Nα-dimethyl-D-phenylalaninamide (2E)-2-butenedioate (2:1)
• Tabimorelin
• N-[(2E)-5-Amino-5-methylhex-2-enoyl]-N-methyl-3-(2-naphthyl)-D-alanyl-N,Nα-dimethyl-D-phenylalaninamide (2E)-but-2-enedioate (2:1)