RSV-IN-2

• 常用名: RSV-IN-2
• 英文名: RSV-IN-2
• CAS号: 2448519-26-2
• 分子量: 539.03
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₃₁ClN₆O₄
• 熔点: N/A
• 闪点: N/A

RSV-IN-2用途

RSV-IN-2是野生型和突变型呼吸道合胞病毒融合蛋白(野生型,EC50=0.27 nM；D486N突变型,EC50=0.70 nM)的有效双重抑制剂。

RSV-IN-2名称

• 英文名: RSV-IN-2

RSV-IN-2生物活性

• 描述: RSV-IN-2是野生型和突变型呼吸道合胞病毒融合蛋白(野生型,EC50=0.27 nM；D486N突变型,EC50=0.70 nM)的有效双重抑制剂。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> RSV
• 参考文献:

  [1]. Yamaguchi-Sasaki T, et al. Discovery of a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins through the modulation of atropisomer interconversion properties. Bioorg Med Chem. 2020 Dec 15;28(24):115818.

RSV-IN-2物理化学性质

• 分子式: C₂₇H₃₁ClN₆O₄
• 分子量: 539.03

RSV-IN-2靶点实验

查看更多实验

实验名称：Major rotational half life in DMSO by spectrophotometry 来源：ChEMBL 靶标：N/A External Id：CHEMBL4705569

实验名称：Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells ass... 来源：ChEMBL 靶标：Fusion glycoprotein F0 External Id：CHEMBL4705571

实验名称：Minor rotational half life in DMSO by spectrophotometry 来源：ChEMBL 靶标：N/A External Id：CHEMBL4705570

实验名称：Protein binding in human plasma at 1 ug/ml incubated for 4 hrs by LC-MS analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL4705575

实验名称：Inhibition of human liver microsomes CYP3A at 10 uM using testosterone as substrate i... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4705574

实验名称：Protein binding in mouse plasma at 1 ug/ml incubated for 4 hrs by LC-MS analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL4705576

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