Antibacterial agent 99

• 常用名: Antibacterial agent 99
• 英文名: Antibacterial agent 99
• CAS号: 2452306-13-5
• 分子量: 459.42
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₇BrN₂
• 熔点: N/A
• 闪点: N/A

Antibacterial agent 99用途

抗菌剂99(化合物7b)是一种强效抗菌剂。抗菌剂99具有显著的抗菌和抗真菌活性。抗菌剂99不显示溶血活性[1]。

Antibacterial agent 99名称

• 英文名: Antibacterial agent 99

Antibacterial agent 99生物活性

• 描述: 抗菌剂99(化合物7b)是一种强效抗菌剂。抗菌剂99具有显著的抗菌和抗真菌活性。抗菌剂99不显示溶血活性[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 体外研究: 抗菌剂99(化合物7b)对Sa-金黄色葡萄球菌(MRSA)ATCC 43300、Ca-白色念珠菌ATCC 90028、Cn-新生隐球菌H99 ATCC 208821的MIC分别为8、8、16μg/mL的抗菌活性【1】。抗菌剂99对HEK293细胞显示细胞毒性,CC50为2.1μg/mL,对人红细胞显示溶血活性,HC10大于32μg/mL。
• 参考文献:

  [1]. Demchenko S, et al. Synthesis, antibacterial and antifungal activity of new 3-biphenyl-3H-Imidazo[1,2-a]azepin-1-ium bromides. Eur J Med Chem. 2020 Sep 1;201:112477.

Antibacterial agent 99物理化学性质

• 分子式: C₂₇H₂₇BrN₂
• 分子量: 459.42

Antibacterial agent 99靶点实验

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实验名称：Cytotoxicity against HEK293 cells measured after 20 hrs by resazurin dye based fluore... 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL4771576

实验名称：Hemolytic activity in human RBC preincubated for 10 mins under shaking condition and ... 来源：ChEMBL 靶标：Erythrocyte External Id：CHEMBL4771577

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 at 32 ug/ml measured after... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL4771570

实验名称：Antibacterial activity against Klebsiella pneumoniae ATCC 700603 at 32 ug/ml measured... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL4771571

实验名称：Antifungal activity against Cryptococcus neoformans ATCC 208821 measured after 24 hrs... 来源：ChEMBL 靶标：Cryptococcus neoformans External Id：CHEMBL4771568

实验名称：Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC 43300... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4771569

实验名称：Antifungal activity against Candida albicans ATCC 90028 at 32 ug/ml measured after 24... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4771574

实验名称：Antifungal activity against Cryptococcus neoformans ATCC 208821 at 32 ug/ml measured ... 来源：ChEMBL 靶标：Cryptococcus neoformans External Id：CHEMBL4771575

实验名称：Antibacterial activity against Acinetobacter baumannii ATCC 19606 at 32 ug/ml measure... 来源：ChEMBL 靶标：Acinetobacter baumannii External Id：CHEMBL4771572

实验名称：Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 32 ug/ml measured... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL4771573

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