星鱼甾醇

• 常用名: 星鱼甾醇
• 英文名: Stellasterol
• CAS号: 2465-11-4
• 分子量: 398.66
• 密度: 1.0±0.1 g/cm3
• 沸点: 487.5±44.0 °C at 760 mmHg
• 分子式: C₂₈H₄₆O
• 熔点: 149-150 °C
• 闪点: 213.0±20.7 °C

星鱼甾醇用途

甾醇是一种天然产物。星甾醇对Bcl-2蛋白具有高亲和力(Ki:118.05nM)。星甾醇是一种弱的α-葡萄糖苷酶抑制剂[1][2]。

星鱼甾醇名称

• 中文名: 星鱼甾醇
• 英文名: 5α-ergosta-7,22-dien-3β-ol

星鱼甾醇生物活性

• 描述: 甾醇是一种天然产物。星甾醇对Bcl-2蛋白具有高亲和力(Ki:118.05nM)。星甾醇是一种弱的α-葡萄糖苷酶抑制剂[1][2]。
• 相关类别:
  信号通路 >> 细胞凋亡 >> Bcl-2家族
  研究领域 >> 其他
• 参考文献:

  [1]. Lau MF, et al. In vitro and in silico anticancer evaluation of a medicinal mushroom, Ganoderma neo-japonicum Imazeki, against human colonic carcinoma cells. Biotechnol Appl Biochem. 2021 Aug;68(4):902-917.

  [2]. Krisyanti Budipramana, et al. An Integrated In Silico and In Vitro Assays of Dipeptidyl Peptidase-4 and α-Glucosidase Inhibition by Stellasterol from Ganoderma austral. Sci. Pharm. 2019, 87(3). 21.

星鱼甾醇物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 487.5±44.0 °C at 760 mmHg
• 熔点: 149-150 °C
• 分子式: C₂₈H₄₆O
• 分子量: 398.66
• 闪点: 213.0±20.7 °C
• 精确质量: 398.354858
• PSA: 20.23000
• LogP: 9.60
• InChIKey: QOXPZVASXWSKKU-UEIWAABPSA-N
• SMILES: CC(C)C(C)C=CC(C)C1CCC2C3=CCC4CC(O)CCC4(C)C3CCC21C
• 蒸汽压: 0.0±2.8 mmHg at 25°C
• 折射率: 1.532
• 储存条件: 2-8°C

星鱼甾醇靶点实验

查看更多实验

实验名称：Therapeutic index, ratio of TC50 for MDCK cells to IC50 for Influenza A virus infecte... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1052280

实验名称：Therapeutic index, ratio of TC50 for human Hep2 cells to IC50 for Parainfluenza virus... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1052278

实验名称：Cytotoxicity against MDCK cells 来源：ChEMBL 靶标：MDCK External Id：CHEMBL1052279

实验名称：Antiviral activity against Parainfluenza virus type 3 infected in human Hep2 cells as... 来源：ChEMBL 靶标：Human respirovirus 3 External Id：CHEMBL1052276

实验名称：Antiviral activity against Influenza A virus infected in MDCK cells assessed as inhib... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL1052277

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 50 uM after 2... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL2340770

实验名称：Cytotoxicity against LPS-stimulated mouse RAW264.7 cells assessed as cell viability a... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL2340769

实验名称：Antiviral activity against influenza A virus infected in MDCK cells 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL998282

实验名称：Antiviral activity against herpes simplex virus 1 infected in MDCK cells 来源：ChEMBL 靶标：Human alphaherpesvirus 1 External Id：CHEMBL998283

实验名称：Hepatoprotective activity in rat WB-F344 cells assessed as inhibition of D-galactosam... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3107128

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星鱼甾醇英文别名

• 5alpha-ergosta-7,22-dien-3beta-ol
• (3β,5α,22E)-Ergosta-7,22-dien-3-ol
• 5α-Ergosta-7,22-dien-3β-ol
• Stellasterol