Zanamivir-Cholesterol Conjugate

• 常用名: Zanamivir-Cholesterol Conjugate
• 英文名: Zanamivir-Cholesterol Conjugate
• CAS号: 2478446-18-1
• 分子量: 1189.52
• 密度: N/A
• 沸点: N/A
• 分子式: C₆₁H₁₀₄N₈O₁₅
• 熔点: N/A
• 闪点: N/A

Zanamivir-Cholesterol Conjugate用途

扎那米韦-胆固醇结合物是一种长效神经氨酸酶抑制剂,对耐药流感病毒具有强大的疗效。

Zanamivir-Cholesterol Conjugate名称

• 英文名: Zanamivir-Cholesterol Conjugate

Zanamivir-Cholesterol Conjugate生物活性

• 描述: 扎那米韦-胆固醇结合物是一种长效神经氨酸酶抑制剂,对耐药流感病毒具有强大的疗效。
• 相关类别:
  信号通路 >> 抗感染 >> 流感病毒
  研究领域 >> 感染
• 参考文献:

  [1]. Lv X, et al. Zanamivir-Cholesterol Conjugate: A Long-Acting Neuraminidase Inhibitor with Potent Efficacy against Drug-Resistant Influenza Viruses. J Med Chem. 2021 Nov 19.

Zanamivir-Cholesterol Conjugate物理化学性质

• 分子式: C₆₁H₁₀₄N₈O₁₅
• 分子量: 1189.52
• InChIKey: HHSAMDIFEWHABO-CENFOOLCSA-N
• SMILES: CC(=O)NC1C(N=C(N)N)C=C(C(=O)O)OC1C(OC(=O)NCCOCCOCCOCCOCCOCCOCc1cn(CCCCCCOC2CCC3(C)C(=CCC4C3CCC3(C)C(C(C)CCCC(C)C)CCC43)C2)nn1)C(O)CO

Zanamivir-Cholesterol Conjugate靶点实验

查看更多实验

实验名称：Drug uptake in MDCK cells assessed as permeability across plasma membrane incubated f... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5036121

实验名称：Protection against Influenza A virus (A/Puerto Rico/8/34 (H1N1)) infected in Balb/c m... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL5036110

实验名称：Protection against Influenza A virus (A/Puerto Rico/8/34 (H1N1)) infected in Balb/c m... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL5036126

实验名称：Protection against Influenza A virus (A/Puerto Rico/8/34 (H1N1)) infected in Balb/c m... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL5036109

实验名称：Half life in Sprague-Dawley rat at 1.7 uM/kg, iv by HPLC analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5036125

实验名称：Protection against Influenza A virus (A/Puerto Rico/8/34 (H1N1)) infected in Balb/c m... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL5036108

实验名称：Oral bioavailability in Sprague-Dawley rat at 1.7 uM/kg by HPLC analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5036124

实验名称：Protection against Influenza A virus (A/Puerto Rico/8/34 (H1N1)) infected in Balb/c m... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL5036129

实验名称：Protection against Influenza A virus (A/Puerto Rico/8/34 (H1N1)) infected in Balb/c m... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL5036128

实验名称：Protection against Influenza A virus (A/California/07/2009 (H1NI)) harboring NA H275Y... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL5036127

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