NPP1-IN-1

• 常用名: NPP1-IN-1
• 英文名: NPP1-IN-1
• CAS号: 2493063-65-1
• 分子量: 391.46
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₁NO₂
• 熔点: N/A
• 闪点: N/A

NPP1-IN-1用途

NPP1-IN-1是一种有效的NPP抑制剂,对NPP1和NPP3的IC50s分别为0.15μM和40μM【1】。

NPP1-IN-1名称

• 英文名: NPP1-IN-1

NPP1-IN-1生物活性

• 描述: NPP1-IN-1是一种有效的NPP抑制剂,对NPP1和NPP3的IC50s分别为0.15μM和40μM【1】。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
  研究领域 >> 代谢疾病
• 靶点实验:

  IC50: 0.15 μM (NPP1), 40 μM (NPP3)[1]

• 参考文献:

  [1]. Ahmad H, Ullah S, Rahman F, et al. Synthesis of biphenyl oxazole derivatives via Suzuki coupling and biological evaluations as nucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors. Eur J Med Chem. 2020;208:112759.

NPP1-IN-1物理化学性质

• 分子式: C₂₇H₂₁NO₂
• 分子量: 391.46

NPP1-IN-1靶点实验

查看更多实验

实验名称：Inhibition of human recombinant NPP1 expressed in COS-7 cell membrane at 100 uM using... 来源：ChEMBL 靶标：Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 External Id：CHEMBL4710183

实验名称：Inhibition of human recombinant NPP3 expressed in COS-7 cell membrane using p-nitroph... 来源：ChEMBL 靶标：Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 External Id：CHEMBL4710186

实验名称：Potency index, ratio of IC50 for suramin to IC50 for test compound for human recombin... 来源：ChEMBL 靶标：Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 External Id：CHEMBL4710187

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