鸦胆子素A

• 常用名: 鸦胆子素A
• 英文名: Bruceine A
• CAS号: 25514-31-2
• 分子量: 522.542
• 密度: 1.4±0.1 g/cm3
• 沸点: 712.6±60.0 °C at 760 mmHg
• 分子式: C₂₆H₃₄O₁₁
• 熔点: N/A
• 闪点: 237.1±26.4 °C

鸦胆子素A用途

Bruceine A(NSC310616; Dihydrobrusatol)是天然的苦木苦味素化合物,由鸦胆子干果实中提取,可作用于犬焦虫症。

鸦胆子素A名称

• 中文名: 鸦胆子素 A
• 英文名: brucein a
• 中文别名: 鸦胆子素A

鸦胆子素A生物活性

• 描述: Bruceine A(NSC310616; Dihydrobrusatol)是天然的苦木苦味素化合物,由鸦胆子干果实中提取,可作用于犬焦虫症。
• 相关类别:
  信号通路 >> 抗感染 >> 寄生物
  研究领域 >> 感染
  天然产物 >> 其他
• 参考文献:

  [1]. Nakao R, et al. Evaluation of efficacy of bruceine A, a natural quassinoid compound extracted from a medicinal plant, Brucea javanica, for canine babesiosis. J Vet Med Sci. 2009 Jan;71(1):33-41.

鸦胆子素A物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 712.6±60.0 °C at 760 mmHg
• 分子式: C₂₆H₃₄O₁₁
• 分子量: 522.542
• 闪点: 237.1±26.4 °C
• 精确质量: 522.210083
• PSA: 165.89000
• LogP: 1.80
• InChIKey: LPZSTPCYWWRQFU-VILODJCFSA-N
• SMILES: COC(=O)C12OCC34C(CC5C(C)=C(O)C(=O)CC5(C)C3C(O)C1O)OC(=O)C(OC(=O)CC(C)C)C24
• 蒸汽压: 0.0±5.2 mmHg at 25°C
• 折射率: 1.596
• 储存条件: -20°C

鸦胆子素A靶点实验

查看更多实验

实验名称：Cytotoxicity against human Lu1 cells after 2 days by sulforhodamine B assay 来源：ChEMBL 靶标：Lu1 External Id：CHEMBL965751

实验名称：Cytotoxicity against hormone-dependent human LNCAP cells after 2 days by sulforhodami... 来源：ChEMBL 靶标：LNCaP External Id：CHEMBL965752

实验名称：Antimalarial activity against multidrug-resistant Plasmodium falciparum K1 infected h... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL1019090

实验名称：Cytotoxicity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay 来源：ChEMBL 靶标：MDA-MB-231 External Id：CHEMBL4712370

实验名称：Cytotoxicity against human MCF-7 cells incubated for 72 hrs by MTT assay 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4712369

实验名称：Antibabesial activity against Babesia gibsoni 来源：ChEMBL 靶标：Babesia gibsoni External Id：CHEMBL925693

实验名称：Antimalarial activity as reduced parasitaemia at day 4 against Plasmodium berghei N i... 来源：ChEMBL 靶标：Plasmodium berghei External Id：CHEMBL1019093

实验名称：Antiamoebic activity against Entamoeba histolytica 来源：ChEMBL 靶标：Entamoeba histolytica External Id：CHEMBL3058937

实验名称：Ratio ED50 for human MCF7 cells to ED50 for human MCF7 cells in presence of 43 uM (-)... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL965755

实验名称：Antimalarial activity as reduced parasitaemia at day 4 against Plasmodium berghei N i... 来源：ChEMBL 靶标：Plasmodium berghei External Id：CHEMBL1019092

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鸦胆子素A英文别名

• Bruceine A
• BRUCEIN A
• Methyl (11β,12α,13β,15β)-3,11,12-trihydroxy-15-[(3-methylbutanoyl)oxy]-2,16-dioxo-13,20-epoxypicras-3-en-21-oate
• Isobruceine A
• 22,23-dihydrobrusatol