N-acetylspermine

• 常用名: N-acetylspermine
• 英文名: N-acetylspermine
• CAS号: 25593-72-0
• 分子量: 244.37700
• 密度: 0.962g/cm3
• 沸点: 442.9ºC at 760 mmHg
• 分子式: C₁₂H₂₈N₄O
• 熔点: N/A
• 闪点: 221.7ºC

N-acetylspermine用途

N1乙酰精胺是尿中存在的内源性代谢产物,可用于白血病的研究[1][2]。

N-acetylspermine名称

• 英文名: N1-acetylspermine

N-acetylspermine生物活性

• 描述: N1乙酰精胺是尿中存在的内源性代谢产物,可用于白血病的研究[1][2]。
• 相关类别:
  研究领域 >> 癌症
• 靶点实验:

  Human Endogenous Metabolite

• 体外研究: 内源性代谢产物被定义为《京都基因和基因组百科全书》注释为我们基因组中约1900种代谢酶的底物或产物。在文献正文中很清楚,许多这些代谢产物都具有毒性[1]。
• 参考文献:

  [1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.

  [2]. Lee SH, et al. Polyamine profiles in the urine of patients with leukemia. Cancer Lett. 1998 Jan 9;122(1-2):1-8.

N-acetylspermine物理化学性质

• 密度: 0.962g/cm3
• 沸点: 442.9ºC at 760 mmHg
• 分子式: C₁₂H₂₈N₄O
• 分子量: 244.37700
• 闪点: 221.7ºC
• 精确质量: 244.22600
• PSA: 82.67000
• LogP: 2.14320
• InChIKey: GUNURVWAJRRUAV-UHFFFAOYSA-N
• SMILES: CC(=O)NCCCNCCCCNCCCN
• 蒸汽压: 4.84E-08mmHg at 25°C
• 折射率: 1.479

N-acetylspermine安全信息

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-36
• 海关编码: 2924199090

N-acetylspermine海关

• 海关编码: 2924199090
• 中文概述: 2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途, 包装
• Summary: 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-acetylspermine靶点实验

查看更多实验

实验名称：Compound was determined for putrescine (PUT) level in murine L1210 cells after treatm... 来源：ChEMBL 靶标：L1210 External Id：CHEMBL703820

实验名称：Compound was determined for spermidine (SPD) level in L1210 cells after treatment at ... 来源：ChEMBL 靶标：L1210 External Id：CHEMBL703822

实验名称：Compound was tested for the enzyme activity against Spermidine/spermine N1-acetyl tra... 来源：ChEMBL 靶标：Diamine acetyltransferase 1 External Id：CHEMBL801414

实验名称：Compound was tested for the enzyme activity against ornithine decarboxylase (ODC) in ... 来源：ChEMBL 靶标：Ornithine decarboxylase External Id：CHEMBL757938

实验名称：Drug level in human HepG2 cells assessed as SSAT2-mediated compound formation treated... 来源：ChEMBL 靶标：Thialysine N-epsilon-acetyltransferase External Id：CHEMBL3541433

实验名称：Activity of Encephalitozoon cuniculi polyamine oxidase assessed as hydrogen peroxide ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1662239

实验名称：Compound was tested for the enzyme activity against S-Adenosyl-methionine decarboxyla... 来源：ChEMBL 靶标：S-adenosylmethionine decarboxylase proenzyme 1 External Id：CHEMBL800459

实验名称：Drug level in human HepG2 cells assessed as SSAT1-mediated compound formation treated... 来源：ChEMBL 靶标：Diamine acetyltransferase 1 External Id：CHEMBL3541434

实验名称：Inhibition of SPD uptake by polyamine transporter of MDA-MB-231 breast carcinoma cell... 来源：ChEMBL 靶标：N/A External Id：CHEMBL765823

实验名称：Effective concentration of compound with DFMO tested in vitro for ability to inhibit ... 来源：ChEMBL 靶标：MDA-MB-231 External Id：CHEMBL707380

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N-acetylspermine英文别名

• N-[3-[4-(3-aminopropylamino)butylamino]propyl]acetamide
• n-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamid
• N'-Monoacetylspermine
• N(1)-acetylspermine
• N-Acetylspermine
• N(1)-Acetylspermine