Anti-MRSA agent 2

• 常用名: Anti-MRSA agent 2
• 英文名: Anti-MRSA agent 2
• CAS号: 2597082-01-2
• 分子量: 430.09
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₀Br₂N₂O
• 熔点: N/A
• 闪点: N/A

Anti-MRSA agent 2用途

抗MRSA试剂2(化合物14)对耐甲氧西林金黄色葡萄球菌(MRSA)具有高度抑制活性,MIC为0.098μg/ml,对正常细胞的细胞毒性相对较低。抗MRSA试剂2具有很强的破坏细菌膜和与基因组DNA结合的能力[1]。

Anti-MRSA agent 2名称

• 英文名: Anti-MRSA agent 2

Anti-MRSA agent 2生物活性

• 描述: 抗MRSA试剂2(化合物14)对耐甲氧西林金黄色葡萄球菌(MRSA)具有高度抑制活性,MIC为0.098μg/ml,对正常细胞的细胞毒性相对较低。抗MRSA试剂2具有很强的破坏细菌膜和与基因组DNA结合的能力[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 靶点实验:

  MIC: 0.098 μg/ml (MRSA)[1]

• 参考文献:

  [1]. Wang X, et al. Fascaplysin derivatives binding to DNA via unique cationic five-ring coplanar backbone showed potent antimicrobial/antibiofilm activity against MRSA in vitro and in vivo. Eur J Med Chem. 2022;230:114099.

Anti-MRSA agent 2物理化学性质

• 分子式: C₁₈H₁₀Br₂N₂O
• 分子量: 430.09

Anti-MRSA agent 2靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell survival at 25 ug/ml incub... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5157533

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell survival at 12.5 ug/ml inc... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5157532

实验名称：Induction of membrane morphological changes in methicillin-resistant Staphylococcus a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5157535

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell survival at 50 ug/ml incub... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5157534

实验名称：Bactericidal activity against methicillin-resistant Staphylococcus aureus ATCC 4330 a... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL5157528

实验名称：Hemolytic activity in mouse erythrocytes assessed as hemolysis at 12.5 ug/ml relative... 来源：ChEMBL 靶标：Erythrocyte External Id：CHEMBL5157531

实验名称：Bactericidal activity against methicillin-resistant Staphylococcus aureus ATCC 4330 a... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL5157530

实验名称：Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 4330 ... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL5157524

实验名称：Bactericidal activity against methicillin-resistant Staphylococcus aureus ATCC 4330 a... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL5157527

实验名称：Bactericidal activity against methicillin-resistant Staphylococcus aureus ATCC 4330 a... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL5157526

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