夫仑替唑

更新时间：2025-08-27 14:04:00

夫仑替唑结构式	常用名	夫仑替唑	英文名	Frentizole
	CAS号	26130-02-9	分子量	299.34800
	密度	1.42g/cm3	沸点	N/A
	分子式	C₁₅H₁₃N₃O₂S	熔点	N/A
	MSDS	N/A	闪点	N/A

夫仑替唑用途

Frentizole是FDA批准的免疫抑制剂,是新型的Aβ-ABAD相互作用抑制剂。

中文名	夫仑替唑
英文名	1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenylurea
英文别名	更多

描述	Frentizole是FDA批准的免疫抑制剂,是新型的Aβ-ABAD相互作用抑制剂。
相关类别	信号通路 >> 神经信号通路 >> β淀粉样蛋白研究领域 >> 炎症/免疫
参考文献	[1]. I I Scheetz ME, D G Carlson, and M R Schinitsky Frentizole, a novel immunosuppressive, and azathioprine: their comparative effects on host resistance to Pseudomonas aeruginosa, Candida albicans, herpes simplex virus, and influenza (Ann Arbor) virus. Infec [2]. Hatfield SM, Hartley LW, Schmidtke JR. The immunomodulatory action of frentizole, a novel immunosuppressive agent. Immunopharmacology. 1982 Dec;5(2):169-79. [3]. Xie, Yuli; Deng, Shixian; Chen, Zhenzhang et al. Identification of small-molecule inhibitors of the Aβ-ABAD interaction. Bioorganic & Medicinal Chemistry Letters (2006), 16(17), 4657-4660.

描述

Frentizole是FDA批准的免疫抑制剂,是新型的Aβ-ABAD相互作用抑制剂。

相关类别

信号通路 >> 神经信号通路 >> β淀粉样蛋白

研究领域 >> 炎症/免疫

参考文献

[1]. I I Scheetz ME, D G Carlson, and M R Schinitsky Frentizole, a novel immunosuppressive, and azathioprine: their comparative effects on host resistance to Pseudomonas aeruginosa, Candida albicans, herpes simplex virus, and influenza (Ann Arbor) virus. Infec

[2]. Hatfield SM, Hartley LW, Schmidtke JR. The immunomodulatory action of frentizole, a novel immunosuppressive agent. Immunopharmacology. 1982 Dec;5(2):169-79.

[3]. Xie, Yuli; Deng, Shixian; Chen, Zhenzhang et al. Identification of small-molecule inhibitors of the Aβ-ABAD interaction. Bioorganic & Medicinal Chemistry Letters (2006), 16(17), 4657-4660.

密度	1.42g/cm3
分子式	C₁₅H₁₃N₃O₂S
分子量	299.34800
精确质量	299.07300
PSA	94.98000
LogP	4.03550
InChIKey	JHBWYQRKOUBPCA-UHFFFAOYSA-N
SMILES	COc1ccc2nc(NC(=O)Nc3ccccc3)sc2c1
折射率	1.752
储存条件	2-8℃

海关编码	2934999090

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
来源：NCGC
External Id：SNCA-p-activity-luciferase

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源：The Scripps Research Institute Molecular Screening Center
靶标：muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
来源：824
External Id：CYP273

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源：The Scripps Research Institute Molecular Screening Center
靶标：muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
来源：NCGC
External Id：HERG01

实验名称：qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
来源：NCGC
靶标：N/A
External Id：SMAD3201

实验名称：uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
来源：Burnham Center for Chemical Genomics
靶标：cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id：SBCCG-A764-CF-PAF-Primary-Assay

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ant...
来源：The Scripps Research Institute Molecular Screening Center
靶标：muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id：CHRM1_ANT_FLUO8_1536_1X%INH PRUN

实验名称：qHTS for Inhibitors of TGF-b
来源：NCGC
靶标：Smad3 [Homo sapiens]
External Id：SMAD3101

实验名称：Inhibition of full length recombinant human GST-tagged Dyrk1B expressed in baculoviru...
来源：ChEMBL
靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1B
External Id：CHEMBL4259472

共422条，当前第1页，共43页