Antibacterial agent 28

• 常用名: Antibacterial agent 28
• 英文名: Antibacterial agent 28
• CAS号: 2673185-41-4
• 分子量: 824.77
• 密度: N/A
• 沸点: N/A
• 分子式: C₄₀H₆₄Br₂N₄O₄
• 熔点: N/A
• 闪点: N/A

Antibacterial agent 28用途

抗菌剂28是对抗MRSA感染的潜在抗菌候选药物(MICs=0.5–2μg/mL)。

Antibacterial agent 28名称

• 英文名: Antibacterial agent 28

Antibacterial agent 28生物活性

• 描述: 抗菌剂28是对抗MRSA感染的潜在抗菌候选药物(MICs=0.5–2μg/mL)。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Guo Y, et al. Development of Membrane-Active Honokiol/Magnolol Amphiphiles as Potent Antibacterial Agents against Methicillin-Resistant Staphylococcus aureus (MRSA). J Med Chem. 2021 Sep 9;64(17):12903-12916.

Antibacterial agent 28物理化学性质

• 分子式: C₄₀H₆₄Br₂N₄O₄
• 分子量: 824.77
• InChIKey: MYPDZWXWFNRRLM-UHFFFAOYSA-O
• SMILES: C=CCc1ccc(OCCC[N+](C)(C)CC(=O)NCCCC)c(-c2ccc(OCCC[N+](C)(C)CC(=O)NCCCC)c(CC=C)c2)c1.[Br-]

Antibacterial agent 28靶点实验

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实验名称：Cytotoxicity against human L02 cells assessed as cell viability at 128 ug/ml incubate... 来源：ChEMBL 靶标：L02 External Id：CHEMBL4832912

实验名称：Induction of membrane morphological changes in methicillin-resistant Staphylococcus a... 来源：ChEMBL 靶标：Cell membrane External Id：CHEMBL4832911

实验名称：Induction of membrane morphological changes in methicillin-resistant Staphylococcus a... 来源：ChEMBL 靶标：Cell membrane External Id：CHEMBL4832910

实验名称：Induction of membrane disruption in methicillin-resistant Staphylococcus aureus clini... 来源：ChEMBL 靶标：Cell membrane External Id：CHEMBL4832909

实验名称：Toxicity in BALB/c mouse assessed as abnormalities and pathological changes in kidney... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4832916

实验名称：Toxicity in BALB/c mouse assessed as abnormalities and pathological changes in spleen... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4832915

实验名称：Toxicity in BALB/c mouse assessed as abnormalities and pathological changes in liver ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4832914

实验名称：Cytotoxicity against human LO2 cells assessed as cell morphology at 128 ug/ml incubat... 来源：ChEMBL 靶标：L02 External Id：CHEMBL4832913

实验名称：Antibiofilm activity against Staphylococcus aureus assessed as destruction of biofilm... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4832904

实验名称：Antibiofilm activity against methicillin-resistant Staphylococcus aureus clinical iso... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4832903

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