α-常春藤皂苷

更新时间：2025-08-20 08:01:15

α-常春藤皂苷结构式	常用名	α-常春藤皂苷	英文名	alpha-Hederin
	CAS号	27013-91-8	分子量	750.956
	密度	1.3±0.1 g/cm3	沸点	849.6±65.0 °C at 760 mmHg
	分子式	C₄₁H₆₆O₁₂	熔点	215ºC (dec.)
	MSDS	中文版美版	闪点	250.7±27.8 °C

α-常春藤皂苷用途

alpha-hederin是能够水溶的五环三萜皂苷,有很多化学特性,例如止痉挛,驱虫,和抑制细胞增长。

中文名	Alpha-常春藤苷
英文名	kalopanaxsaponin A
中文别名	a-常春藤皂苷 \| 常春藤皂甙 \| Alpha-常春藤皂苷 \| α-常春藤皂苷 \| alpha-常春藤皂甙
英文别名	更多

描述	alpha-hederin是能够水溶的五环三萜皂苷,有很多化学特性,例如止痉挛,驱虫,和抑制细胞增长。
相关类别	信号通路 >> 其他 >> 其他天然产物 >> 萜类化合物和糖苷研究领域 >> 其他
参考文献	[1]. Danloy S et al. Effects of alpha-hederin, a saponin extracted from Hedera helix, on cells cultured in vitro. Planta Med, 1994 Feb, 60(1):45-9. [2]. Maryam Fallahi et al. Effect of Alpha-Hederin, the active constituent of Nigella sativa, on miRNA-126, IL-13 mRNA levels and inflammation of lungs in ovalbumin-sensitized male rats. Planta Med, 1994 Feb, 60(1):45-9.

描述

alpha-hederin是能够水溶的五环三萜皂苷,有很多化学特性,例如止痉挛,驱虫,和抑制细胞增长。

相关类别

信号通路 >> 其他 >> 其他

天然产物 >> 萜类化合物和糖苷

研究领域 >> 其他

参考文献

[1]. Danloy S et al. Effects of alpha-hederin, a saponin extracted from Hedera helix, on cells cultured in vitro. Planta Med, 1994 Feb, 60(1):45-9.

[2]. Maryam Fallahi et al. Effect of Alpha-Hederin, the active constituent of Nigella sativa, on miRNA-126, IL-13 mRNA levels and inflammation of lungs in ovalbumin-sensitized male rats. Planta Med, 1994 Feb, 60(1):45-9.

密度	1.3±0.1 g/cm3
沸点	849.6±65.0 °C at 760 mmHg
熔点	215ºC (dec.)
分子式	C₄₁H₆₆O₁₂
分子量	750.956
闪点	250.7±27.8 °C
精确质量	750.455444
PSA	195.60000
LogP	8.37
InChIKey	KEOITPILCOILGM-JAVOQYPHSA-N
SMILES	CC1OC(OC2C(OC3CCC4(C)C(CCC5(C)C4CC=C4C6CC(C)(C)CCC6(C(=O)O)CCC45C)C3(C)CO)OCC(O)C2O)C(O)C(O)C1O
外观性状	白色粉末
蒸汽压	0.0±0.6 mmHg at 25°C
折射率	1.601
储存条件	2~8℃

α-常春藤皂苷毒性英文版

危害码 (欧洲)	Xi
风险声明 (欧洲)	22
安全声明 (欧洲)	22-45-24/25
危险品运输编码	UN 1544
RTECS号	RK0177800

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Induction of highly curved structures in relation to membrane permeabilization and budding by the triterpenoid saponins, α- and δ-Hederin.

J. Biol. Chem. 288(20) , 14000-17, (2013)

The interactions of triterpenoid monodesmosidic saponins, α-hederin and δ-hederin, with lipid membranes are involved in their permeabilizing effect. Unfortunately, the interactions of these saponins w...

Alpha-hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors.

Biochemistry 48(15) , 3477-82, (2009)

Hederacoside C, alpha-hederin, and hederagenin are saponins of dry extracts obtained from the leaves of ivy (Hedera helix L.). Internalization of beta(2)-adrenergic receptor-GFP fusion proteins after ...

Participation of cholinergic pathways in α-hederin-induced contraction of rat isolated stomach strips.

Phytomedicine 19(7) , 591-5, (2012)

The dry extract of Hedra helix leaves and its main active compounds, predominantly α-hederin and hederacoside C, has been traditionally believed to act spasmolytic. However, it has been recently prove...

α-Hederin

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UNII:4H15F0GLV2

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