ACSS2-IN-1

• 常用名: ACSS2-IN-1
• 英文名: ACSS2-IN-1
• CAS号: 2711039-08-4
• 分子量: 500.98
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₅ClN₆O₂
• 熔点: N/A
• 闪点: N/A

ACSS2-IN-1用途

ACSS2-IN-1是治疗癌症的有效ACSS2抑制剂。ACSS2-IN-1(CPM1)是一种有效的ACSS2抑制剂。ACSS2-IN-1抑制ACSS2,IC50为0.01 nM至<1 nM。ACSS2-IN-1可用于癌症研究[1]。

ACSS2-IN-1名称

• 英文名: ACSS2-IN-1

ACSS2-IN-1生物活性

• 描述: ACSS2-IN-1是治疗癌症的有效ACSS2抑制剂。ACSS2-IN-1(CPM1)是一种有效的ACSS2抑制剂。ACSS2-IN-1抑制ACSS2,IC50为0.01 nM至<1 nM。ACSS2-IN-1可用于癌症研究[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 抗感染 >> RSV
• 参考文献:

  [1]. Ram W Sabnis. Amide-Substituted Condensed Pyridine Derivatives as ACSS2 Inhibitors for Treating Cancer.ACS Med Chem Lett. 2021 Nov 8;12(12):1870-1871.

ACSS2-IN-1物理化学性质

• 分子式: C₂₇H₂₅ClN₆O₂
• 分子量: 500.98
• InChIKey: WLUNFHGEBAZYCQ-UHFFFAOYSA-N
• SMILES: CCc1c(C(O)(c2ccccc2)c2ccccc2)nn2cc(Cl)c(C(=O)Nc3ncn(CC)n3)cc12

ACSS2-IN-1靶点实验

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实验名称：Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incor... 来源：ChEMBL 靶标：Acetyl-coenzyme A synthetase, cytoplasmic External Id：CHEMBL4831474

实验名称：Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incor... 来源：ChEMBL 靶标：Acetyl-coenzyme A synthetase, cytoplasmic External Id：CHEMBL4831473

实验名称：Biochemical Activity ACSS2 Assay from US Patent US20230271956: "AMIDE DERIVATIVES" 来源：BindingDB 靶标：N/A External Id：BindingDB_9026_1

实验名称：Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assay 来源：ChEMBL 靶标：Acetyl-coenzyme A synthetase, cytoplasmic External Id：CHEMBL4831472

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