Cap-dependent endonuclease-IN-21

• 常用名: Cap-dependent endonuclease-IN-21
• 英文名: Cap-dependent endonuclease-IN-21
• CAS号: 2741952-35-0
• 分子量: 527.47
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₃F₂N₃O₇
• 熔点: N/A
• 闪点: N/A

Cap-dependent endonuclease-IN-21用途

Cap依赖性内切酶-IN-21是Cap依赖性内切酶(CEN)的有效抑制剂。Cap依赖性内切酶-IN-21抑制流感病毒的复制。ap依赖性内切酶-IN-21具有研究流感病毒感染(A型流感)的潜力(摘自专利WO2021233302A1,化合物8B或8A)[1]。

Cap-dependent endonuclease-IN-21名称

• 英文名: Cap-dependent endonuclease-IN-21

Cap-dependent endonuclease-IN-21生物活性

• 描述: Cap依赖性内切酶-IN-21是Cap依赖性内切酶(CEN)的有效抑制剂。Cap依赖性内切酶-IN-21抑制流感病毒的复制。ap依赖性内切酶-IN-21具有研究流感病毒感染(A型流感)的潜力(摘自专利WO2021233302A1,化合物8B或8A)[1]。
• 相关类别:
  信号通路 >> 抗感染 >> 流感病毒
  研究领域 >> 感染
• 参考文献:

  [1]. Shuhui Chen, et al. Fused ring derivatives and their pharmaceutical applications. Patent WO2021233302A1.

Cap-dependent endonuclease-IN-21物理化学性质

• 分子式: C₂₆H₂₃F₂N₃O₇
• 分子量: 527.47
• InChIKey: NKFNQBUTOXCBGL-FCHUYYIVSA-N
• SMILES: COC(=O)OCOc1c2n(ccc1=O)N1C(c3ccccc3)c3cc(F)c(F)cc3OCCC1N(C)C2=O

Cap-dependent endonuclease-IN-21靶点实验

查看更多实验

实验名称：Antiviral activity against Influenza A virus A/PR/8/34 infected in BALB/c mouse asses... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL5529577

实验名称：Antiviral activity against Influenza A virus A/PR/8/34 infected in BALB/c mouse asses... 来源：ChEMBL 靶标：Influenza A virus External Id：CHEMBL5529576

实验名称：Prodrug conversion in cynomolgus monkey assessed as (7aS,16R)-2,3-difluoro-10-hydroxy... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5529572

实验名称：Prodrug conversion in cynomolgus monkey assessed as (7aS,16R)-2,3-difluoro-10-hydroxy... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5529571

实验名称：Prodrug conversion in Beagle dog assessed as (7aS,16R)-2,3-difluoro-10-hydroxy-8-meth... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5529569

实验名称：Prodrug conversion in Beagle dog assessed as (7aS,16R)-2,3-difluoro-10-hydroxy-8-meth... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5529568

实验名称：Prodrug conversion in BALB/c mouse assessed as (7aS,16R)-2,3-difluoro-10-hydroxy-8-me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5529566

实验名称：Prodrug conversion in BALB/c mouse infected with Influenza B virus B/Lee/40 assessed ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5529581

实验名称：Prodrug conversion in BALB/c mouse assessed as (7aS,16R)-2,3-difluoro-10-hydroxy-8-me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5529565

实验名称：Antiviral activity against Influenza B virus B/Lee/40 infected in BALB/c mouse assess... 来源：ChEMBL 靶标：Influenza B virus External Id：CHEMBL5529580

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