Resigratinib

• 常用名: Resigratinib
• 英文名: Resigratinib
• CAS号: 2750709-91-0
• 分子量: 523.53
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₇F₂N₇O₃
• 熔点: N/A
• 闪点: N/A

Resigratinib用途

雷西替尼(KIN-3248)是一种FGFR酪氨酸激酶抑制剂,具有抗肿瘤作用[1]。

Resigratinib名称

• 英文名: Resigratinib

Resigratinib生物活性

• 描述: 雷西替尼(KIN-3248)是一种FGFR酪氨酸激酶抑制剂,具有抗肿瘤作用[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 蛋白酪氨酸激酶 >> FGFR
• 参考文献:

  [1]. Franovic, et al. Treatment of cancer with an FGFR kinase inhibitor. World Intellectual Property Organization, WO2023107979 A1 2023-06-15.

Resigratinib物理化学性质

• 分子式: C₂₆H₂₇F₂N₇O₃
• 分子量: 523.53
• InChIKey: YXVDEILMUVTDMK-JKSUJKDBSA-N
• SMILES: C=CC(=O)N1CC(n2nc(C#Cc3c(F)cc4c(ncn4C4CC4)c3F)c(C(N)=O)c2NC)CC1COC

Resigratinib靶点实验

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实验名称：Solubility of compound in SGF 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541376

实验名称：Solubility of compound in FaSSIF 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541377

实验名称：Solubility of compound in FeSSIF 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541378

实验名称：Inhibition of FGFR1 (unknown origin) at 1 uM relative to control 来源：ChEMBL 靶标：Fibroblast growth factor receptor 1 External Id：CHEMBL5541379

实验名称：Inhibition of FGFR1 V561M mutant (unknown origin) at 1 uM relative to control 来源：ChEMBL 靶标：Fibroblast growth factor receptor 1 External Id：CHEMBL5541380

实验名称：Inhibition of FGFR2 (unknown origin) at 1 uM relative to control 来源：ChEMBL 靶标：Fibroblast growth factor receptor 2 External Id：CHEMBL5541381

实验名称：Inhibition of FGFR2 V564I mutant (unknown origin) at 1 uM relative to control 来源：ChEMBL 靶标：Fibroblast growth factor receptor 2 External Id：CHEMBL5541382

实验名称：Inhibition of FGFR3 (unknown origin) at 1 uM relative to control 来源：ChEMBL 靶标：Fibroblast growth factor receptor 3 External Id：CHEMBL5541383

实验名称：Inhibition of FGFR3 K650E mutant (unknown origin) at 1 uM relative to control 来源：ChEMBL 靶标：Fibroblast growth factor receptor 3 External Id：CHEMBL5541384

实验名称：Inhibition of FGFR3 K650M mutant (unknown origin) at 1 uM relative to control 来源：ChEMBL 靶标：Fibroblast growth factor receptor 3 External Id：CHEMBL5541385

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