mGluR5 antagonist-1

• 常用名: mGluR5 antagonist-1
• 英文名: mGluR5 antagonist-1
• CAS号: 2761424-76-2
• 分子量: 382.41
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₁₈N₄O₂
• 熔点: N/A
• 闪点: N/A

mGluR5 antagonist-1用途

mGluR5antagonist-1 是一种高亲和力 mGluR5 拮抗剂,IC50 值为 11.5 nM。mGluR5 拮抗剂-1 具有抗抑郁作用。

mGluR5 antagonist-1名称

• 英文名: mGluR5 antagonist-1

mGluR5 antagonist-1生物活性

• 描述: mGluR5antagonist-1 是一种高亲和力 mGluR5 拮抗剂,IC50 值为 11.5 nM。mGluR5 拮抗剂-1 具有抗抑郁作用。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 谷氨酸受体
• 参考文献:

  [1]. Yonglei Du, et al. Novel substituted 4-(Arylethynyl)-Pyrrolo[2,3-d]pyrimidines negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 5 (mGlu5) Treat depressive disorder in mice. Eur J Med Chem. 2023.

mGluR5 antagonist-1物理化学性质

• 分子式: C₂₃H₁₈N₄O₂
• 分子量: 382.41

mGluR5 antagonist-1靶点实验

查看更多实验

实验名称：Antidepressant activity in chronic unpredictable mild stress induced depression C57BL... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5637342

实验名称：Antidepressant activity in chronic unpredictable mild stress induced depression C57BL... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5637343

实验名称：Antidepressant activity in chronic unpredictable mild stress induced depression C57BL... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5637344

实验名称：Antidepressant activity in chronic unpredictable mild stress induced depression C57BL... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5637347

实验名称：Antidepressant activity in chronic unpredictable mild stress induced depression C57BL... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5637348

实验名称：Antidepressant activity in chronic unpredictable mild stress induced depression C57BL... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5637349

实验名称：Antidepressant activity in chronic unpredictable mild stress induced depression C57BL... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5637350

实验名称：Antidepressant activity in chronic unpredictable mild stress induced depression C57BL... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5637351

实验名称：Antidepressant activity in chronic unpredictable mild stress induced depression C57BL... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5637352

实验名称：Antidepressant activity in chronic unpredictable mild stress induced depression C57BL... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5637353

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