PBRM1-BD2-IN-4

• 常用名: PBRM1-BD2-IN-4
• 英文名: PBRM1-BD2-IN-4
• CAS号: 2819989-60-9
• 分子量: 272.73
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₅H₁₃ClN₂O
• 熔点: N/A
• 闪点: N/A

PBRM1-BD2-IN-4用途

PBRM1-BD2-IN-4(化合物15)是一种有效的PBRM1-溴代甲烷抑制剂,PBRM1-BD 2和PBRM1-BD5的Kd值分别为5.5μM和11.1μM,PBRM2-BD2的IC50值为0.2μM。

PBRM1-BD2-IN-4名称

• 英文名: PBRM1-BD2-IN-4

PBRM1-BD2-IN-4生物活性

• 描述: PBRM1-BD2-IN-4(化合物15)是一种有效的PBRM1-溴代甲烷抑制剂,PBRM1-BD 2和PBRM1-BD5的Kd值分别为5.5μM和11.1μM,PBRM2-BD2的IC50值为0.2μM。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 表观遗传学 >> 表观遗传读者域
• 靶点实验:

  Kd: 5.5 μM (PBRM1-BD2), 11.1 μM (PBRM1-BD5)[1] IC50: 0.2 μM (PBRM1-BD2)[1]

PBRM1-BD2-IN-4物理化学性质

• 分子式: C₁₅H₁₃ClN₂O
• 分子量: 272.73
• InChIKey: ZDFFMEAQARQRHC-UHFFFAOYSA-N
• SMILES: Cc1ccccc1C1NC(=O)c2c(Cl)cccc2N1

PBRM1-BD2-IN-4靶点实验

查看更多实验

实验名称：Binding affinity to N-terminal His-TEV-tagged human SMARCA4 transfected in Escherichi... 来源：ChEMBL 靶标：Transcription activator BRG1 External Id：CHEMBL5112698

实验名称：Binding affinity to N-terminal His6-TEV-tagged human SMARCA2B transfected in Escheric... 来源：ChEMBL 靶标：Probable global transcription activator SNF2L2 External Id：CHEMBL5112699

实验名称：Binding affinity to N-terminal His-TEV-tagged human GCN5 transfected in Escherichia c... 来源：ChEMBL 靶标：Histone acetyltransferase KAT2A External Id：CHEMBL5112694

实验名称：Binding affinity to N-terminal His-TEV-tagged human BRWD1-BD2 transfected in Escheric... 来源：ChEMBL 靶标：Bromodomain and WD repeat-containing protein 1 External Id：CHEMBL5112695

实验名称：Binding affinity to N-terminal His-TEV-tagged human PHIP-BD2 transfected in Escherich... 来源：ChEMBL 靶标：PH-interacting protein External Id：CHEMBL5112696

实验名称：Binding affinity to N-terminal His-TEV-tagged human BPTF-BD2 transfected in Escherich... 来源：ChEMBL 靶标：Nucleosome-remodeling factor subunit BPTF External Id：CHEMBL5112697

实验名称：Binding affinity to N-terminal His6-TEV-tagged human TRIM33B transfected in Escherich... 来源：ChEMBL 靶标：E3 ubiquitin-protein ligase TRIM33 External Id：CHEMBL5112690

实验名称：Binding affinity to N-terminal His-TEV-tagged human ATAD2B transfected in Escherichia... 来源：ChEMBL 靶标：ATPase family AAA domain-containing protein 2B External Id：CHEMBL5112691

实验名称：Binding affinity to N-terminal His-TEV-tagged human BRD1 transfected in Escherichia c... 来源：ChEMBL 靶标：Bromodomain-containing protein 1 External Id：CHEMBL5112692

实验名称：Binding affinity to N-terminal His6-TEV-tagged human BRPF1 bromodomain transfected in... 来源：ChEMBL 靶标：Peregrin External Id：CHEMBL5112693

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