天芥菜碱

• 常用名: 天芥菜碱
• 英文名: Heliotrine
• CAS号: 303-33-3
• 分子量: 313.389
• 密度: 1.2±0.1 g/cm3
• 沸点: 450.7±45.0 °C at 760 mmHg
• 分子式: C₁₆H₂₇NO₅
• 熔点: 125-126 °C
• 闪点: 226.4±28.7 °C

天芥菜碱用途

Heliotrine 是一种单酯吡咯烷核生物碱,用于获得肝炎和肝硬化的模型。

天芥菜碱名称

• 中文名: 7S-天芥菜碱
• 英文名: heliotrine
• 中文别名: 天芥菜碱

天芥菜碱生物活性

• 描述: Heliotrine 是一种单酯吡咯烷核生物碱,用于获得肝炎和肝硬化的模型。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. R Schoental, et al. Pancreatic Islet-Cell and Other Tumors in Rats Given Heliotrine, a Monoester Pyrrolizidine Alkaloid, and Nicotinamide. Cancer Res. 1975 Aug;35(8):2020-4.

天芥菜碱物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 450.7±45.0 °C at 760 mmHg
• 熔点: 125-126 °C
• 分子式: C₁₆H₂₇NO₅
• 分子量: 313.389
• 闪点: 226.4±28.7 °C
• 精确质量: 313.188934
• PSA: 79.23000
• LogP: 1.04
• InChIKey: LMFKRLGHEKVMNT-UJDVCPFMSA-N
• SMILES: COC(C)C(O)(C(=O)OCC1=CCN2CCC(O)C12)C(C)C
• 外观性状: 粉末
• 蒸汽压: 0.0±2.5 mmHg at 25°C
• 折射率: 1.541
• 储存条件: 2-8°C， 密封， 干燥， 避光

天芥菜碱毒性和生态

天芥菜碱安全信息

• 安全声明 (欧洲): 22-36/37/39-45
• 危险品运输编码: UN 1544
• 包装等级: III
• 危险类别: 6.1(b)

天芥菜碱靶点实验

查看更多实验

实验名称：Nematicidal activity against juvenile stage of Rhabditis sp. assessed as inhibition o... 来源：ChEMBL 靶标：Rhabditis sp. External Id：CHEMBL3080873

实验名称：Nematicidal activity against juvenile stage of Pratylenchus penetrans assessed as inh... 来源：ChEMBL 靶标：Pratylenchus penetrans External Id：CHEMBL3080875

实验名称：Nematicidal activity against juvenile stage of Meloidogyne incognita (root-knot nemat... 来源：ChEMBL 靶标：Meloidogyne incognita External Id：CHEMBL3080876

实验名称：Nematicidal activity against juvenile stage of Heterodera schachtii assessed as inhib... 来源：ChEMBL 靶标：Heterodera schachtii External Id：CHEMBL3080877

实验名称：Nematicidal activity against juvenile stage of Rhabditis sp. assessed as inhibition o... 来源：ChEMBL 靶标：Rhabditis sp. External Id：CHEMBL3080879

实验名称：Nematicidal activity against juvenile stage of Pratylenchus penetrans assessed as inh... 来源：ChEMBL 靶标：Pratylenchus penetrans External Id：CHEMBL3080880

实验名称：Nematicidal activity against juvenile stage of Meloidogyne incognita (root-knot nemat... 来源：ChEMBL 靶标：Meloidogyne incognita External Id：CHEMBL3080881

实验名称：Nematicidal activity against juvenile stage of Heterodera schachtii assessed as inhib... 来源：ChEMBL 靶标：Heterodera schachtii External Id：CHEMBL3080882

实验名称：Nematicidal activity against juvenile stage of Rhabditis sp. assessed as reduction of... 来源：ChEMBL 靶标：Rhabditis sp. External Id：CHEMBL3071261

实验名称：Nematicidal activity against juvenile stage of Rhabditis sp. assessed as reduction of... 来源：ChEMBL 靶标：Rhabditis sp. External Id：CHEMBL3071262

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天芥菜碱英文别名

• (2S,3R)-2-Hydroxy-2-isopropyl-3-methoxy-buttersaeure-((7aR)-7c-hydroxy-(7ar)-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethylester)
• (2S)-2-Hydroxy-2-[(R)-1-methoxyethyl]-3-methylbutyric acid [(1S,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl
• (2S,3R)-2-hydroxy-2-isopropyl-3-methoxy-butyric acid-((7aR)-7c-hydroxy-(7ar)-5,6,7,7a-tetrahydro-3H-pyrrolizin-1-ylmethyl ester)
• 7S-Heliotrine
• [(1S,7aR)-1-Hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl (2S,3R)-2-hydroxy-2-isopropyl-3-methoxybutanoate
• Heliotrine
• (2S)-2-Hydroxy-2-[(R)-1-methoxyethyl]-3-methylbutyric acid [(1S,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester
• Heliotrin
• 9-Heliotrylheliotridine