谷氨酰胺酶C-IN-1

• 常用名: 谷氨酰胺酶C-IN-1
• 英文名: Glutaminase C-IN-1
• CAS号: 311795-38-7
• 分子量: 475.42000
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₇BrN₂O
• 熔点: N/A
• 闪点: N/A

谷氨酰胺酶C-IN-1用途

Glutaminase C-IN-1 (968)是Glutaminase C变构抑制剂。

谷氨酰胺酶C-IN-1名称

• 中文名: 5-[3-溴-4-(二甲胺基)苯基]-2,3,5,6-四氢-2,2-二甲基苯并[A]菲啶-4(1H)-酮
• 英文名: 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one

谷氨酰胺酶C-IN-1生物活性

• 描述: Glutaminase C-IN-1 (968)是Glutaminase C变构抑制剂。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 癌症
• 参考文献:

  [1]. Stalnecker CA, et al. Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):394-9.

谷氨酰胺酶C-IN-1物理化学性质

• 分子式: C₂₇H₂₇BrN₂O
• 分子量: 475.42000
• 精确质量: 474.13100
• PSA: 32.34000
• LogP: 7.11580
• InChIKey: NVFRRJQWRZFDLM-UHFFFAOYSA-N
• SMILES: CN(C)c1ccc(C2Nc3ccc4ccccc4c3C3=C2C(=O)CC(C)(C)C3)cc1Br
• 储存条件: 2-8℃

谷氨酰胺酶C-IN-1安全信息

• 危害声明: H413
• 危险品运输编码: NONH for all modes of transport

谷氨酰胺酶C-IN-1靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Primary qHTS for Identification of Small Molecule Activators of Huntingtin-Antisense ... 来源：NCGC External Id：huntington-HTTAS8-p1-FF-overN

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_OPM1-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-OC1MY5-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-KMS_34-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_L363-m4-1

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谷氨酰胺酶C-IN-1英文别名

• QC-219
• 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]phenanthridin-4(1H)-one
• Glutaminase C-IN-1