L-5-甲基四氢叶酸-13C,d3

• 常用名: L-5-甲基四氢叶酸-13C,d3
• 英文名: Levomefolic acid
• CAS号: 31690-09-2
• 分子量: 459.456
• 密度: 1.6±0.1 g/cm3
• 沸点: N/A
• 分子式: C₂₀H₂₅N₇O₆
• 熔点: N/A
• 闪点: N/A

L-5-甲基四氢叶酸-13C,d3用途

Levomefolic acid (5-MTHF)是天然的叶酸活性形式。

L-5-甲基四氢叶酸-13C,d3名称

• 中文名: L-5-甲基四氢叶酸
• 英文名: (S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
• 中文别名: 左美福酸

L-5-甲基四氢叶酸-13C,d3生物活性

• 描述: Levomefolic acid (5-MTHF)是天然的叶酸活性形式。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> 叶酸
  研究领域 >> 癌症
• 参考文献:

  [1]. Hirsch S, Miranda D, Mu?oz E, et al. Natural killer cell cytotoxicity is not regulated by folic acid in vitro. Nutrition. 2013 Jan 9. pii: S0899-9007(12)00404-2.

  [2]. Liu Y, Green TJ, Wong P, Kitts DD. Microencapsulation of L-5-methyltetrahydrofolic Acid with ascorbate improves stability in baked bread products. J Agric Food Chem. 2013 Jan 9;61(1):247-54.

  [3]. Merola N, Alonso FJ, Ros G, Castón MJ. Antioxidant activity comparison between [6S]-5-methyltetrahydrofolic acid calcium salt and the related racemate form. Food Chem. 2013 Jan 15;136(2):984-8.

  [4]. Liu Y, Tomiuk S, Rozoy E, et al. Thermal oxidation studies on reduced folate, L-5-methyltetrahydrofolic acid (L-5-MTHF) and strategies for stabilization using food matrices. J Food Sci. 2012 Feb;77(2):C236-43.

  [5]. Bashir M Rezka, Guido R.M.M Haenena, Wim J.F van der Vijgha, et al. Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore. 2003,555(3):601-605.

  [6]. Levomefolic acid

L-5-甲基四氢叶酸-13C,d3物理化学性质

• 密度: 1.6±0.1 g/cm3
• 分子式: C₂₀H₂₅N₇O₆
• 分子量: 459.456
• 精确质量: 459.186646
• PSA: 202.77000
• LogP: -2.61
• 折射率: 1.733
• 储存条件: 2-8℃，密封，干燥，对空气敏感

L-5-甲基四氢叶酸-13C,d3靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ... 来源：NCGC External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) naive MV4-11 ce... 来源：NCGC External Id：s-sky_synergy-MV-411_N-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

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L-5-甲基四氢叶酸-13C,d3英文别名

• N-(5-methyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
• N-[4-({[(6S)-2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]-L-glutamic acid
• L-5-methyltetrahydrofolic acid
• (6S)-5-Methyltetrahydrofolic acid
• 5-Methyl-(6S)-tetrahydrofolic acid
• 5-Methyltetrahydrofolate
• L-5-Methyltetrahydrofolate
• Levomefolic acid
• Levomefolic Acid (See also L375720)
• N-[4-({[(6S)-2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
• 5-methyltetrahydrofolic acid
• levomefolinic acid
• (2S)-2-{[4-({[(6S)-2-Amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentanedioic acid