Beta-d-N4-hydroxycytidine

• 常用名: Beta-d-N4-hydroxycytidine
• 英文名: Beta-d-N4-hydroxycytidine
• CAS号: 3258-02-4
• 分子量: 259.21600
• 密度: N/A
• 沸点: N/A
• 分子式: C₉H₁₃N₃O₆
• 熔点: N/A
• 闪点: N/A

Beta-d-N4-hydroxycytidine用途

Beta-d-N4-hydroxycytidine 是一种非常有效的抗委内瑞拉马脑炎病毒剂 (anti-VEEV) ，EC50， EC90 和 EC99 分别为 0.426，1.036 和 2.5 μM。

Beta-d-N4-hydroxycytidine名称

• 英文名: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one

Beta-d-N4-hydroxycytidine生物活性

• 描述: Beta-d-N4-hydroxycytidine 是一种非常有效的抗委内瑞拉马脑炎病毒剂 (anti-VEEV) ,EC50, EC90 和 EC99 分别为 0.426,1.036 和 2.5 μM。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Urakova N, et al. β-d-N⁴-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome. J Virol. 2018 Jan 17;92(3). pii: e01965-17.

Beta-d-N4-hydroxycytidine物理化学性质

• 分子式: C₉H₁₃N₃O₆
• 分子量: 259.21600
• 精确质量: 259.08000
• PSA: 137.07000
• InChIKey: XCUAIINAJCDIPM-XVFCMESISA-N
• SMILES: O=c1nc(NO)ccn1C1OC(CO)C(O)C1O
• 外观性状: 固体;White to Light yellow powder to crystal
• 储存条件: -20°C;存放于惰性气体之中;避免空气,湿气 (吸湿),加热

Beta-d-N4-hydroxycytidine靶点实验

查看更多实验

实验名称：Antiviral activity against wild type SARS CoV-2 infected in Vero E6 cells transfected... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL5112762

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实验名称：Cytotoxicity against African green monkey Vero E6 cells transfected with TMPRSS2 asse... 来源：ChEMBL 靶标：Vero C1008 External Id：CHEMBL5112764

实验名称：Antiviral activity against SARS CoV infected in HEK293T cells transfected with ACE2 a... 来源：ChEMBL 靶标：Severe acute respiratory syndrome-related coronavirus External Id：CHEMBL5112765

实验名称：Antiviral activity against SARS CoV-2 delta TY11-927 infected in HEK293T cells transf... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL5112758

实验名称：Half life in CD1 mouse at 150 mg/kg, po administered as single dose by LC-MS/MS analy... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5137627

实验名称：Antiviral activity against SARS CoV-2 omicron TY38-873 BA.1 variant infected in HEK29... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL5112759

实验名称：Half life in CD1 mouse at 500 mg/kg, po administered as single dose by LC-MS/MS analy... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5137628

实验名称：Antiviral activity against SARS CoV-2 omicron TY38-873 BA.2 variant infected in HEK29... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL5112760

实验名称：Substrate activity at human mARC1 expressed in Escherichia coli assessed as turnover ... 来源：ChEMBL 靶标：Mitochondrial amidoxime-reducing component 1 External Id：CHEMBL4614164

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Beta-d-N4-hydroxycytidine英文别名

• Uridine,4-oxime
• N4-Hydroxycytidine
• Cytidine,N-hydroxy
• 4-N-Hydroxycytidine
• EIDD-1931