松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇

• 常用名: 松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇
• 英文名: Coniferyl alcohol
• CAS号: 32811-40-8
• 分子量: 180.20000
• 密度: 1.1272g/ml
• 沸点: N/A
• 分子式: C₁₀H₁₂O₃
• 熔点: 75-76℃
• 闪点: N/A

用途

(E) -松柏醇是松柏醇的异构体。松柏醇是丁香酚、二苯乙烯类化合物和香豆素生物合成的中间产物。松柏醇特异性抑制真菌生长[1][2]。

名称

• 中文名: 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇
• 英文名: 4-[(1E)-3-Hydroxy-1-propen-1-yl]-2-methoxyphenol

生物活性

• 描述: (E) -松柏醇是松柏醇的异构体。松柏醇是丁香酚、二苯乙烯类化合物和香豆素生物合成的中间产物。松柏醇特异性抑制真菌生长[1][2]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
• 靶点实验:

  Human Endogenous Metabolite

• 参考文献:

  [1]. Keeling CI, et al. New components of the honey bee (Apis mellifera L.) queen retinue pheromone. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4486-91.

  [2]. König S, et al. Soluble phenylpropanoids are involved in the defense response of Arabidopsis against Verticillium longisporum. New Phytol. 2014 May;202(3):823-37.

物理化学性质

• 密度: 1.1272g/ml
• 熔点: 75-76℃
• 分子式: C₁₀H₁₂O₃
• 分子量: 180.20000
• 精确质量: 180.07900
• PSA: 49.69000
• LogP: 1.40630
• InChIKey: JMFRWRFFLBVWSI-NSCUHMNNSA-N
• SMILES: COc1cc(C=CCO)ccc1O
• 外观性状: 油状物体
• 储存条件: 20°C，避光，惰性气体

安全信息

• 危害码 (欧洲): Xi

靶点实验

查看更多实验

实验名称：Protection against IR-induced mortality in ICR mouse assessed as increase in mean sur... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4192885

实验名称：Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as i... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3864552

实验名称：Activation of HSF1 in MEF assessed as protection against IR-induced caspase3 cleavage... 来源：ChEMBL 靶标：Heat shock factor protein 1 External Id：CHEMBL4192884

实验名称：Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as i... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3864553

实验名称：Protection against IR-induced reduction of food and water intake in ICR mouse at 5 to... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4192887

实验名称：Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as i... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3864554

实验名称：Toxicity in ICR mouse at 10 mg/kg, ip measured within 30 days 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4192886

实验名称：Activation of HSF1 in MEF assessed as protection against cisplatin-induced PARP cleav... 来源：ChEMBL 靶标：Heat shock factor protein 1 External Id：CHEMBL4192881

实验名称：ERK5 transcriptional activity HTS 来源：24565 靶标：N/A External Id：ERK5 transcriptional activity-HTS

实验名称：Activation of HSF1 in MEF assessed as protection against paclitaxel-induced caspase3 ... 来源：ChEMBL 靶标：Heat shock factor protein 1 External Id：CHEMBL4192880

共68条，当前第1页，共7页

1

2

3

4

5

英文别名

• trans-coniferyl alcohol
• Coniferol
• Coniferylic alcohol
• (E)-4-(3-hydroxyprop-1-enyl)-2-methoxyphenol
• p-Coniferyl alcohol
• G-HYDROXY ISOEUGENOL
• 4-hydroxy-3-methoxybenzyl alcohol
• CONIFERYL ALCOHOL(RG)
• trans-3-(4-hydroxy-3-methoxyphenyl)-2-propenol
• 4-[(1E)-3-hydroxy-prop-1-enyl]-2-methoxyphenol