NBD-557

Q: NBD-557的储存条件是什么？

NBD-557储存条件：-20°C。

更新时间：2026-07-18 01:28:57

NBD-557结构式	常用名	NBD-557	英文名	NBD-557
	CAS号	333352-59-3	分子量	382.29500
	密度	N/A	沸点	N/A
	分子式	C₁₇H₂₄BrN₃O₂	熔点	N/A
	MSDS	N/A	闪点	N/A

NBD-557用途

NBD-557是HIV-1抑制剂。

本表展示该化学物质的中文名称、英文系统名、各类中文与英文别名信息。

中文名	NBD-557
英文名	N'-(4-bromophenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide
英文别名	更多

本表记录该化合物相关生物活性、作用靶点、活性说明与生物实验相关数据。

描述	NBD-557是HIV-1抑制剂。
相关类别	信号通路 >> 抗感染 >> HIV 研究领域 >> 感染
参考文献	[1]. Sch?n A, Madani N, Klein JC, Hubicki A, Ng D, Yang X, Smith AB 3rd, Sodroski J, Freire E. Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120. Biochemistry. 2006 Sep 12;45(36):10973-80. [2]. Singh IP, Chauthe SK. Small molecule HIV entry inhibitors: Part II. Attachment and fusion inhibitors: 2004-2010. Expert Opin Ther Pat. 2011 Mar;21(3):399-416. [3]. Zhao Q, Ma L, Jiang S, Lu H, Liu S, He Y, Strick N, Neamati N, Debnath AK. Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4. Virology. 2005 Sep 1;339 [4]. Narumi, Tetsuo et al. CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist. Bioorganic & Medicinal Chemistry Letters (2010), 20(19), 5853-5858.

描述

NBD-557是HIV-1抑制剂。

相关类别

信号通路 >> 抗感染 >> HIV

研究领域 >> 感染

参考文献

[1]. Sch?n A, Madani N, Klein JC, Hubicki A, Ng D, Yang X, Smith AB 3rd, Sodroski J, Freire E. Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120. Biochemistry. 2006 Sep 12;45(36):10973-80.

[2]. Singh IP, Chauthe SK. Small molecule HIV entry inhibitors: Part II. Attachment and fusion inhibitors: 2004-2010. Expert Opin Ther Pat. 2011 Mar;21(3):399-416.

[3]. Zhao Q, Ma L, Jiang S, Lu H, Liu S, He Y, Strick N, Neamati N, Debnath AK. Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4. Virology. 2005 Sep 1;339

[4]. Narumi, Tetsuo et al. CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist. Bioorganic & Medicinal Chemistry Letters (2010), 20(19), 5853-5858.

本表包含该物质理化参数，如熔点、沸点、密度、溶解度、旋光性等理化指标，无数据项标记为N/A。

分子式	C₁₇H₂₄BrN₃O₂
分子量	382.29500
精确质量	381.10500
PSA	73.72000
LogP	4.18220
InChIKey	QQRFLGRIDNNARB-UHFFFAOYSA-N
SMILES	CC1(C)CC(NC(=O)C(=O)Nc2ccc(Br)cc2)CC(C)(C)N1
储存条件	-20°C

本表记录该化合物靶点、体外体内实验、生物测定实验相关实验数据。

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (...
来源：NCGC
External Id：IP6K1-p1

实验名称：Cytotoxicity against human PM1 cells expressing CCR5 by MTT assay
来源：ChEMBL
靶标：N/A
External Id：CHEMBL1259501

实验名称：Antiviral activity against HIV1 MNA infected in human PM1 cells expressing CCR5 asses...
来源：ChEMBL
靶标：Human immunodeficiency virus 1
External Id：CHEMBL1259500

实验名称：Antiviral activity against HIV1 KYAG primary isolate assessed as inhibition of virus-...
来源：ChEMBL
靶标：Human immunodeficiency virus 1
External Id：CHEMBL1065278

实验名称：Cytotoxicity against mock-infected CCR5 expressing human PM1 cells by MTT assay
来源：ChEMBL
靶标：N/A
External Id：CHEMBL1065279

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu...
来源：NCGC
External Id：CYP3A4437

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu...
来源：NCGC
External Id：CYP2D6395

实验名称：HIV Enzyme Data
来源：NIAID
靶标：N/A
External Id：HIV Enzyme Data

实验名称：qHTS for characterization and localization of zebrafish homologs of the human ABCB1 m...
来源：NCGC
靶标：N/A
External Id：mdr-f13-vec

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu...
来源：NCGC
External Id：CYP2C9536

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本表罗列该化合物全部英文别名、系统命名、CAS别名等英文名称集合。

nbd-557

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本部分为该化合物相关常见问答，包含基础参数、性状、储存条件等高频咨询问题与对应答案。

Q: 333352-59-3的中文名称是什么？