Tomentosin

• 常用名: Tomentosin
• 英文名: Tomentosin
• CAS号: 33649-15-9
• 分子量: 248.318
• 密度: 1.1±0.1 g/cm3
• 沸点: 416.2±45.0 °C at 760 mmHg
• 分子式: C₁₅H₂₀O₃
• 熔点: N/A
• 闪点: 185.1±28.8 °C

Tomentosin用途

Tomentosin是一种抗炎的倍半萜内酯,可从因纽拉隼中分离出来。Tomentosi可诱导细胞凋亡,抑制胰腺癌细胞的增殖、迁移和侵袭[1]。

Tomentosin名称

• 英文名: Tomentosin

Tomentosin生物活性

• 描述: Tomentosin是一种抗炎的倍半萜内酯,可从因纽拉隼中分离出来。Tomentosi可诱导细胞凋亡,抑制胰腺癌细胞的增殖、迁移和侵袭[1]。
• 相关类别:
  信号通路 >> 细胞凋亡 >> 细胞凋亡
  研究领域 >> 癌症
• 参考文献:

  [1]. Güçlü E, et al. Tomentosin induces apoptosis in pancreatic cancer cells through increasing reactive oxygen species and decreasing mitochondrial membrane potential. Toxicol In Vitro. 2022 Oct;84:105458.

Tomentosin物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 416.2±45.0 °C at 760 mmHg
• 分子式: C₁₅H₂₀O₃
• 分子量: 248.318
• 闪点: 185.1±28.8 °C
• 精确质量: 248.141251
• LogP: 2.12
• InChIKey: AVFIYMSJDDGDBQ-CUOATXAZSA-N
• SMILES: C=C1C(=O)OC2CC(C)C(CCC(C)=O)=CCC12
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.511

Tomentosin靶点实验

查看更多实验

实验名称：Antifungal activity against Candida albicans SC5314 by CLSI standard M27-A3 method 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL3632325

实验名称：Cytotoxicity against mouse RAW264.7 cells at antiinflammatory IC50 level by MTT assay 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL1912246

实验名称：Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL1912245

实验名称：Antifungal activity against Candida albicans SC5314 assessed as inhibition of yeast c... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL3632327

实验名称：Antifungal activity against Candida albicans SC5314 assessed as inhibition of biofilm... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL3632326

实验名称：Inhibition of LPS-induced NO production in mouse RAW264.7 cells incubated for 24 hrs ... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4717861

实验名称：Cytotoxicity against mouse RAW264.7 cells at concentration required inhibit NO synthe... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL1168032

实验名称：Inhibition of LPS-induced NO production in mouse RAW264.7 cells measured after 24 hrs 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL1168031

实验名称：Cytostatic activity against human HT-29 cells incubated for 72 hrs by alamar blue rea... 来源：ChEMBL 靶标：HT-29 External Id：CHEMBL3595842

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3595843

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Tomentosin英文别名

• Xanthalongin
• Tomentosin
• (3aR,7S,8aR)-7-Methyl-3-methylene-6-(3-oxobutyl)-3,3a,4,7,8,8a-hexahydro-2H-cyclohepta[b]furan-2-one