1-BCP

• 常用名: 1-BCP
• 英文名: 1-BCP
• CAS号: 34023-62-6
• 分子量: 233.26
• 密度: 1.256g/cm3
• 沸点: 406.9ºC at 760mmHg
• 分子式: C₁₃H₁₅NO₃
• 熔点: N/A
• 闪点: 199.9ºC

1-BCP用途

1-BCP 是一种中枢活性药物,调节AMPA 受体的门控电流。1-BCP 是一种可增强记忆的药物。

1-BCP名称

• 中文名: 1-BCP
• 英文名: 1,3-benzodioxol-5-yl(piperidin-1-yl)methanone

1-BCP生物活性

• 描述: 1-BCP 是一种中枢活性药物,调节AMPA 受体的门控电流。1-BCP 是一种可增强记忆的药物。
• 相关类别:
  信号通路 >> 神经信号通路 >> iGluR
  研究领域 >> 神经疾病
  信号通路 >> 跨膜转运 >> iGluR
• 靶点实验:

  AMPA receptor[1].

• 参考文献:

  [1]. Arai A, et al. A centrally active drug that modulates AMPA receptor gated currents. Brain Res. 1994 Feb 28;638(1-2):343-6.

  [2]. Desai MA, et al. 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices. Neuropharmacology. 1995 Feb;34(2):141-7.

1-BCP物理化学性质

• 密度: 1.256g/cm3
• 沸点: 406.9ºC at 760mmHg
• 分子式: C₁₃H₁₅NO₃
• 分子量: 233.26
• 闪点: 199.9ºC
• 精确质量: 233.10500
• PSA: 38.77000
• LogP: 1.97930
• InChIKey: BXBNADAPIHHXJQ-UHFFFAOYSA-N
• SMILES: O=C(c1ccc2c(c1)OCO2)N1CCCCC1
• 折射率: 1.587
• 储存条件: -20°C，密闭，干燥

1-BCP毒性和生态

1-BCP安全信息

• 海关编码: 2934999090

1-BCP海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-BCP靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：Compound was evaluated to potentiate response of AMPA-activated current in Xenopus oo... 来源：ChEMBL 靶标：Glutamate receptor 1 External Id：CHEMBL700583

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Tocris HTS for Inhibitors of Aerobactin Synthetase lucA 来源：23265 External Id：IucA Pilot Assay Tocris Library

实验名称：qHTS for inhibitors of Vif-A3G interactions: Validation 来源：NCGC 靶标：DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] External Id：VIFG001

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

实验名称：EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Rea... 来源：Broad Institute 靶标：histone-lysine N-methyltransferase EZH2 isoform a [Homo sapiens] External Id：2125-01_Inhibitor_SinglePoint_HTS_Activity

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1-BCP英文别名

• 1-BCP
• 1-piperonyloyl-piperidine
• 1,3-BYCP
• 1-Piperonyloyl-piperidin
• BA 14