5-羟基吡嗪-2-羧酸

• 常用名: 5-羟基吡嗪-2-羧酸
• 英文名: 5-Hydroxypyrazine-2-carboxylic acid
• CAS号: 34604-60-9
• 分子量: 140.097
• 密度: 1.6±0.1 g/cm3
• 沸点: 608.5ºC at 760 mmHg
• 分子式: C₅H₄N₂O₃
• 熔点: >295°C (dec.)
• 闪点: 321.8ºC

5-羟基吡嗪-2-羧酸用途

5-hydroxypyrazine-2-carboxylic acid是抗肺结核化合物pyrazinamide (PZA)的代谢产物。

5-羟基吡嗪-2-羧酸名称

• 中文名: 5-羟基吡嗪-2-羧酸
• 英文名: 5-Hydroxypyrazine-2-carboxylic acid
• 中文别名: 5-羟基-2-羧酸吡嗪 | 5-羟基-2-甲酸吡嗪 | 5-羟基-2-羧酸吡嗪 | 5-羟基-2-吡嗪羧酸 | -羟基吡嗪-2-羧酸

5-羟基吡嗪-2-羧酸生物活性

• 描述: 5-hydroxypyrazine-2-carboxylic acid是抗肺结核化合物pyrazinamide (PZA)的代谢产物。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 其他
• 参考文献:

  [1]. Huq, Fazlul; Hossain, Zahed. Molecular modelling analysis of the metabolism of pyrazinamide. Journal of Pharmacology and Toxicology (2006), 1(6), 505-515.

  [2]. Mehmedagic, Aida; Verite, Philippe; Menager, Sabine et al. Investigation of the effects of concomitant caffeine administration on the metabolic disposition of pyrazinamide in rats. Biopharmaceutics & Drug Disposition (2002), 23(5), 191-195.

5-羟基吡嗪-2-羧酸物理化学性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 608.5ºC at 760 mmHg
• 熔点: >295°C (dec.)
• 分子式: C₅H₄N₂O₃
• 分子量: 140.097
• 闪点: 321.8ºC
• 精确质量: 140.022186
• PSA: 83.31000
• LogP: -1.71
• InChIKey: CGQFCIHUUCMACC-UHFFFAOYSA-N
• SMILES: O=C(O)c1c[nH]c(=O)cn1
• 外观性状: 褐色粉末
• 折射率: 1.662
• 储存条件: 室温

5-羟基吡嗪-2-羧酸MSDS

5-羟基吡嗪-2-羧酸MSDS英文版

5-羟基吡嗪-2-羧酸安全信息

• 危害码 (欧洲): Xi:Irritant
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S36
• 海关编码: 2933990090

5-羟基吡嗪-2-羧酸海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-羟基吡嗪-2-羧酸靶点实验

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实验名称：Antimycobacterial activity against Mycobacterium bovis BCG Pasteur ATCC35734 assessed... 来源：ChEMBL 靶标：Mycobacterium tuberculosis variant bovis External Id：CHEMBL5099097

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5-羟基吡嗪-2-羧酸英文别名

• 5-hydroxyopyrazine-2-carboxylic acid
• 5-hydroxy-pyrazine-2-carboxylic acid
• 2-Carboxy-5-hydroxypyrazine
• 5-hydroxypyrazinoic acid
• 5-Hydroxypyrazine-2-carboxylic acid
• 5-Hydroxy-2-pyrazinecarboxylic acid
• 5-hydroxy-2-pyrazinedicarboxylic acid
• 5-Oxo-4,5-dihydro-2-pyrazinecarboxylic acid
• 6-Hydroxy-3-pyridazinecarboxylic acid
• 5-Hydroxypyrazinecarboxylic Acid
• 5-HYDROXYPYRAZINE-3-CARBOXYLIC ACID
• 5-Hydroxypyrazinoic acid-13C3
• 5-Hydropyrazine-2-carboxylic acid
• 5-oxo-4,5-dihydro-pyrazine-2-carboxylic acid
• MFCD00190599