氯丝菌素

• 常用名: 氯丝菌素
• 英文名: chlorothricin
• CAS号: 34707-92-1
• 分子量: 955.479
• 密度: 1.4±0.1 g/cm3
• 沸点: 1050.8±65.0 °C at 760 mmHg
• 分子式: C₅₀H₆₃ClO₁₆
• 熔点: N/A
• 闪点: 589.3±34.3 °C

氯丝菌素用途

氯菊酯是一种抗生素,是猪心苹果酸脱氢酶的抑制剂[1]。

氯丝菌素名称

• 中文名: 氯丝菌素
• 英文名: Chlorothricin

氯丝菌素生物活性

• 描述: 氯菊酯是一种抗生素,是猪心苹果酸脱氢酶的抑制剂[1]。
• 相关类别:
  研究领域 >> 感染
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. P W Schindler, et al. Chlorothricin, and inhibitor of porcine-heart malate dehydrogenases, discriminating between the mitochondrial and cytoplasmic isoenzyme. Eur J Biochem. 1975 Feb 21;51(2):579-85.

氯丝菌素物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 1050.8±65.0 °C at 760 mmHg
• 分子式: C₅₀H₆₃ClO₁₆
• 分子量: 955.479
• 闪点: 589.3±34.3 °C
• 精确质量: 954.380493
• PSA: 223.04000
• LogP: 9.13
• InChIKey: WUXHQHDSSKBJFH-DELKKKATSA-N
• SMILES: COc1ccc(Cl)c(C)c1C(=O)OC1CC(OC2C(O)CC(OC3CCCC4C3C=CC3CCCCC=CC5C=C(C(=O)O)C(C)CC56OC(=O)C(=C6O)OC(=O)C34C)OC2C)OC(C)C1O
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.619

氯丝菌素英文别名

• Diuresal
• (1S,3R,6R,7E,13R,16S,17S,21R,22R)-17-({4-O-[3-O-(3-Chloro-6-methoxy-2-methylbenzoyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]-2,6-dideoxy-β-D-arabino-hexopyranosyl}oxy)-28-hydroxy-3,22-dimethyl-23,26-dioxo-24,27-dioxapentacyclo[23.2.1.0.0.0]octacosa-4,7,14,25(28)-tetraene-4-carboxylic acid
• Chlorothiazid
• Chlotride
• chlorothiazide
• Chlorthiazide
• (1S,3R,6R,7E,13R,16S,17S,21R,22R)-17-({4-O-[3-O-(3-Chloro-6-methoxy-2-methylbenzoyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]-2,6-dideoxy-β-D-arabino-hexopyranosyl}oxy)-28-hydroxy-3,22-dimethyl-23 ,26-dioxo-24,27-dioxapentacyclo[23.2.1.0.0.0]octacosa-4,7,14,25(28)-tetraene-4-carboxylic acid
• Diuril
• chlorothricin
• Chlorosal
• Chlortiazid
• Clotride
• 6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide,1,1-dioxide
• Chlorurit