Androgen receptor antagonist 3

• 常用名: Androgen receptor antagonist 3
• 英文名: Androgen receptor antagonist 3
• CAS号: 353484-46-5
• 分子量: 331.84
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₁₈ClN
• 熔点: N/A
• 闪点: N/A

Androgen receptor antagonist 3用途

雄激素受体拮抗剂3(化合物C18)是一种雄激素受体(AR)拮抗剂,IC50为2.4μM。雄激素受体拮抗剂3具有抗癌活性[1]。

Androgen receptor antagonist 3名称

• 英文名: Androgen receptor antagonist 3

Androgen receptor antagonist 3生物活性

• 描述: 雄激素受体拮抗剂3(化合物C18)是一种雄激素受体(AR)拮抗剂,IC50为2.4μM。雄激素受体拮抗剂3具有抗癌活性[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 雄激素受体
• 靶点实验:

  IC50: 2.4 μM (Androgen receptor)[1]

• 参考文献:

  [1]. Tang Q, et al. Novel androgen receptor antagonist identified by structure-based virtual screening, structural optimization, and biological evaluation. Eur J Med Chem. 2020 Apr 15;192:112156.

Androgen receptor antagonist 3物理化学性质

• 分子式: C₂₂H₁₈ClN
• 分子量: 331.84

Androgen receptor antagonist 3靶点实验

查看更多实验

实验名称：Displacement of fluormone-AL green from GST-tagged androgen receptor LBD (unknown ori... 来源：ChEMBL 靶标：Androgen receptor External Id：CHEMBL4685674

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability at 5... 来源：ChEMBL 靶标：NIH3T3 External Id：CHEMBL4685680

实验名称：Antiproliferative activity against human PC-3 cells assessed as reduction in cell pro... 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL4685683

实验名称：Antiproliferative activity against human LNCaP C4-2 cells assessed as reduction in ce... 来源：ChEMBL 靶标：LNCaP C4-2 External Id：CHEMBL4685685

实验名称：High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS1303

实验名称：Antiproliferative activity against human DU-145 cells assessed as reduction in cell p... 来源：ChEMBL 靶标：DU-145 External Id：CHEMBL4685684

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

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