Ac-Nle-Pro-Nle-Asp-AMC

• 常用名: Ac-Nle-Pro-Nle-Asp-AMC
• 英文名: Ac-Nle-Pro-Nle-Asp-AMC
• CAS号: 355140-49-7
• 分子量: 655.739
• 密度: 1.3±0.1 g/cm3
• 沸点: 902.2±75.0 °C at 760 mmHg
• 分子式: C₃₃H₄₅N₅O₉
• 熔点: N/A
• 闪点: 499.4±37.1 °C

Ac-Nle-Pro-Nle-Asp-AMC用途

Ac-Nle Pro-Nle Asp-AMC是26S蛋白酶体的特异性底物。Ac Nle Pro Nle Asp AMC可用于26S蛋白酶体半胱天冬酶样活性分析[1][2][3]。

Ac-Nle-Pro-Nle-Asp-AMC名称

• 英文名: Ac-Nle-Pro-Nle-Asp-AMC

Ac-Nle-Pro-Nle-Asp-AMC生物活性

• 描述: Ac-Nle Pro-Nle Asp-AMC是26S蛋白酶体的特异性底物。Ac Nle Pro Nle Asp AMC可用于26S蛋白酶体半胱天冬酶样活性分析[1][2][3]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 代谢酶/蛋白酶 >> 蛋白酶体
• 参考文献:

  [1]. Dunlop RA, et al. The impact of specific oxidized amino acids on protein turnover in J774 cells. Biochem J. 2008 Feb 15;410(1):131-40.

  [2]. Kirk-Ballard H, et al. An extract of Artemisia dracunculus L. inhibits ubiquitin-proteasome activity and preserves skeletal muscle mass in a murine model of diabetes. PLoS One. 2013;8(2):e57112.

  [3]. Pakavathkumar P, et al. Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine. Sci Rep. 2015 Sep 24;5:13730.

Ac-Nle-Pro-Nle-Asp-AMC物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 902.2±75.0 °C at 760 mmHg
• 分子式: C₃₃H₄₅N₅O₉
• 分子量: 655.739
• 闪点: 499.4±37.1 °C
• 精确质量: 655.321716
• LogP: 6.08
• InChIKey: WPTAROWBMZVECB-CQJMVLFOSA-N
• SMILES: CCCCC(NC(=O)C1CCCN1C(=O)C(CCCC)NC(C)=O)C(=O)NC(CC(=O)O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.617

Ac-Nle-Pro-Nle-Asp-AMC英文别名

• (3S)-4-Hydroxy-3-({(2S)-1-hydroxy-2-[(hydroxy{(2S)-1-[N-(1-hydroxyethylidene)-L-norleucyl]-2-pyrrolidinyl}methylene)amino]hexylidene}amino)-4-[(4-methyl-2-oxo-2H-chromen-7-yl)imino]butanoic acid