15-酮-前列腺素F2α

• 常用名: 15-酮-前列腺素F2α
• 英文名: 15-oxoprostaglandin F2α
• CAS号: 35850-13-6
• 分子量: 352.465
• 密度: 1.1±0.1 g/cm3
• 沸点: 535.2±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₂O₅
• 熔点: N/A
• 闪点: 291.5±26.6 °C

15-酮-前列腺素F2α用途

15-酮-前列腺素F2α(15-keto-PGF2α)是前列腺素F2 a的代谢产物。前列腺素F2α。前列腺素F2α是一种口服有效的前列腺素F(PGF)受体(FP受体)激动剂,在分娩的开始和进展中起关键作用[1]。

15-酮-前列腺素F2α名称

• 中文名: 15-酮前列腺素 F2Alpha
• 英文名: 15-oxo-prostaglandin F2α

15-酮-前列腺素F2α生物活性

• 描述: 15-酮-前列腺素F2α(15-keto-PGF2α)是前列腺素F2 a的代谢产物。前列腺素F2α。前列腺素F2α是一种口服有效的前列腺素F(PGF)受体(FP受体)激动剂,在分娩的开始和进展中起关键作用[1]。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 前列腺素受体
• 靶点实验:

  Human Endogenous Metabolite

• 参考文献:

  [1]. S Basu. Radioimmunoassay of 15-keto-13,14-dihydro-prostaglandin F2alpha: an index for inflammation via cyclooxygenase catalysed lipid peroxidation. Prostaglandins Leukot Essent Fatty Acids. 1998 May;58(5):347-52.

15-酮-前列腺素F2α物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 535.2±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₂O₅
• 分子量: 352.465
• 闪点: 291.5±26.6 °C
• 精确质量: 352.224976
• PSA: 94.83000
• LogP: 1.84
• InChIKey: LOLJEILMPWPILA-AMFHKTBMSA-N
• SMILES: CCCCCC(=O)C=CC1C(O)CC(O)C1CC=CCCCC(=O)O
• 蒸汽压: 0.0±3.2 mmHg at 25°C
• 折射率: 1.561
• 储存条件: -20°C

15-酮-前列腺素F2α靶点实验

查看更多实验

实验名称：GPR151 activator identification: cell-based high-throughput counter-screen assay 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Glucose-dependent insulinotropic receptor; AltName: Full=G-protein coupled receptor 119 External Id：GPR119_PHUNTER_AG_LUMI_1536_3X%ACT CSRUN1

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：GPR151 activator identification: cell-based high-throughput confirmation assay 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_3X%ACT CRUN1

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：qHTS for Inhibitors of binding or entry into cells for Marburg Virus 来源：NCGC 靶标：gene 4 small orf - Marburg virus External Id：VSVM-OFFLINE

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

实验名称：qHTS for Inhibitors of binding or entry into cells for Lassa Virus 来源：NCGC 靶标：N/A External Id：VSVL-OFFLINE

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15-酮-前列腺素F2α英文别名

• 15-oxoprostaglandin F2α
• 15-oxo-prostaglandin F2α
• 15-oxo-prostaglandin F2alpha
• (5Z,9α,11α,13E)-9,11-Dihydroxy-15-oxoprosta-5,13-dien-1-oic acid
• 15-ketoprostaglandin F2A
• 15-Ketoprostaglandinef2alpha
• 9ALPHA,11ALPHA-DIHYDROXY-15-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID
• 15-KETO PROSTAGLANDIN F2ALPHA
• 15-Keto PGF2a