二丁酰环磷腺苷钙

• 常用名: 二丁酰环磷腺苷钙
• 英文名: Bucladesine
• CAS号: 362-74-3
• 分子量: 469.386
• 密度: 1.7±0.1 g/cm3
• 沸点: N/A
• 分子式: C₁₈H₂₄N₅O₈P
• 熔点: 203 - 205 °C
• 闪点: N/A

二丁酰环磷腺苷钙用途

Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. Bucladesine is a phosphodiesterase inhibitor. Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations. The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.

二丁酰环磷腺苷钙名称

• 中文名: 二丁酰环磷腺苷
• 英文名: Bucladesine
• 中文别名: 二丁酰环磷腺甙 | 布拉地新

二丁酰环磷腺苷钙物理化学性质

• 密度: 1.7±0.1 g/cm3
• 熔点: 203 - 205 °C
• 分子式: C₁₈H₂₄N₅O₈P
• 分子量: 469.386
• 精确质量: 469.136261
• PSA: 173.80000
• LogP: 1.76300
• InChIKey: CJGYSWNGNKCJSB-YVLZZHOMSA-N
• SMILES: CCCC(=O)Nc1ncnc2c1ncn2C1OC2COP(=O)(O)OC2C1OC(=O)CCC
• 折射率: 1.717
• 储存条件: 室温

二丁酰环磷腺苷钙毒性和生态

二丁酰环磷腺苷钙靶点实验

查看更多实验

实验名称：Neuroprotective activity in Sprague-Dawley rat DA neuron death PD model assessed as i... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4431933

实验名称：Neuroprotective activity in Sprague-Dawley rat astrocytes assessed as effect on vimen... 来源：ChEMBL 靶标：Astrocyte External Id：CHEMBL4431914

实验名称：Neuroprotective activity in Sprague-Dawley rat DA neuron death PD model assessed as s... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4431910

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：qHTS assay for identifying genotoxic compounds that show differential cytotoxicity ag... 来源：824 靶标：N/A External Id：DT40657

实验名称：Induction of autophagy in human SK-N-SH cells expressing EGFP-HDQ74 assessed as reduc... 来源：ChEMBL 靶标：SK-N-SH External Id：CHEMBL1253026

实验名称：Induction of autophagy in rat stable inducible PC12 cells expressing A53T alpha-synuc... 来源：ChEMBL 靶标：PC-12 External Id：CHEMBL1253025

实验名称：qHTS assay for identifying genotoxic compounds that show differential cytotoxicity ag... 来源：824 靶标：N/A External Id：DT40653

实验名称：qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signa... 来源：824 External Id：ARN311

实验名称：qHTS assay to identify small molecule antagonists of the androgen receptor (AR) sign... 来源：824 靶标：N/A External Id：ARV616

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二丁酰环磷腺苷钙英文别名

• dibutyryl cAMP
• Bt2 cyclic AMP
• (4aR,6R,7R,7aR)-6-[6-(butanoylamino)-9H-purin-9-yl]-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl butanoate
• 3',5'-Cyclic AMP dibutyrate
• n-6,o-2'-dibutyryl adenosine cyclic 3':5'-monophosphate
• Cyclic AMP dibutyrate
• N-(9-b-D-Ribofuranosyl-9H-purin-6-yl)butyramide Cyclic 3',5'-(Hydrogen Phosphate) 2'-Butyrate
• N6,2'-O-Dibutyryl cAMP
• N6,2'-O-Dibutyryladenosine 3',5'-Cyclic Monophosphate
• Butanoic acid, (4aR,6R,7R,7aR)-tetrahydro-2-hydroxy-2-oxido-6-[6-[(1-oxobutyl)amino]-9H-purin-9-yl]-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-7-yl ester
• N6,2'-O-dibutyryl-cAMP
• Bucladesine
• (4aR,6R,7R,7aR)-6-[6-(Butyrylamino)-9H-purin-9-yl]-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl butyrate
• Dibutyryl cyclic 3',5'-AMP
• dibutyryl cyclic AMP
• CalciuM Dibutyacyladenosine
• N,O-dibutyryl cyclic AMP
• N-(9-beta-D-Ribofuranosyl-9H-furin-6-yl)-butyramidecyclic3',5'-(hydrogenphosphate)2'-butyrate
• N-(1-Oxobutyl)adenosine Cyclic 3',5'-(Hydrogen Phosphate) 2'-Butanoate
• Dibutyryl-cAMP
• Dibutyryl 3',5'-Cyclic AMP