RBC10

• 常用名: RBC10
• 英文名: RBC10
• CAS号: 362503-73-9
• 分子量: 408.92
• 密度: 1.3±0.1 g/cm3
• 沸点: 616.3±55.0 °C at 760 mmHg
• 分子式: C₂₄H₂₅ClN₂O₂
• 熔点: N/A
• 闪点: 326.5±31.5 °C

RBC10用途

RBC10是一种抗癌剂。RBC10抑制Ral与其效应子RALBP1的结合。RBC10还抑制Ral介导的小鼠胚胎成纤维细胞的细胞扩散和人类癌细胞系的锚定非依赖性生长[1]。

RBC10名称

• 英文名: 11-(2-Chlorophenyl)-10-pentanoyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

RBC10生物活性

• 描述: RBC10是一种抗癌剂。RBC10抑制Ral与其效应子RALBP1的结合。RBC10还抑制Ral介导的小鼠胚胎成纤维细胞的细胞扩散和人类癌细胞系的锚定非依赖性生长[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 拉斯
• 参考文献:

  [1]. Yan C, et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014;515(7527):443-447.

RBC10物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 616.3±55.0 °C at 760 mmHg
• 分子式: C₂₄H₂₅ClN₂O₂
• 分子量: 408.92
• 闪点: 326.5±31.5 °C
• 精确质量: 408.160461
• LogP: 5.00
• InChIKey: XERBEDAMDXRGFD-UHFFFAOYSA-N
• SMILES: CCCCC(=O)N1c2ccccc2NC2=C(C(=O)CCC2)C1c1ccccc1Cl
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.637

RBC10靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ... 来源：NCGC External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

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RBC10英文别名

• 11-(2-Chlorophenyl)-10-pentanoyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one