ACTH(4-10)(人类)

更新时间：2025-08-23 00:31:43

ACTH(4-10)(人类)结构式	常用名	ACTH(4-10)(人类)	英文名	ACTH (4-10)
	CAS号	4037-01-8	分子量	962.09
	密度	1.48g/cm3	沸点	N/A
	分子式	C₄₄H₅₉N₁₃O₁₀S	熔点	N/A
	MSDS	美版	闪点	N/A

ACTH(4-10)(人类)用途

Adrenocorticotropic Hormone (ACTH) (1-39), rat 是一种有效的黑皮质素 4 型受体 (melanocortin 4 receptor, MC4R) 激动剂。

中文名	促肾上腺皮质激素(ACTH)(4-10),人
英文名	met-glu-his-phe-arg-trp-gly
英文别名	更多

描述	Adrenocorticotropic Hormone (ACTH) (1-39), rat 是一种有效的黑皮质素 4 型受体 (melanocortin 4 receptor, MC4R) 激动剂。
相关类别	信号通路 >> 其他 >> 其他多肽产品研究领域 >> 代谢疾病
靶点	Melanocortin 4 receptor[1]
体外研究	促肾上腺皮质激素(ACTH)(4-10),人(ACTH(4-10))是所有黑皮质素的核心序列,并选择性地与MC4-R结合。在人类中,ACTH(4-10)在鼻内应用后进入脑液室,并在连续治疗6周后导致总体脂肪减少[1]。
参考文献	[1]. Wellhöner P, et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue. Int J Obes (Lond). 2012 May;36(5):703-8.

密度	1.48g/cm3
分子式	C₄₄H₅₉N₁₃O₁₀S
分子量	962.09
PSA	183.70000
LogP	9.43540
蒸汽压	4.64E-09mmHg at 25°C
折射率	1.547
储存条件	-20°C，密闭，干燥

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport
WGK德国	3

Ligand-dependent activation of the melanocortin 5 receptor: cAMP production and ryanodine receptor-dependent elevations of [Ca(2+)](I).

Biochem. Biophys. Res. Commun. 290 , 844-850, (2002)

The melanocortins are involved in the regulation of various cognitive and physiological processes such as learning, feeding, immune suppression, pigmentation, and sebum production. Five melanocortin r...

Sniffing neuropeptides: a transnasal approach to the human brain.

Nat. Neurosci. 5(6) , 514-6, (2002)

The melanocortin melanocyte-stimulating hormone/adrenocorticotropin(4-10) decreases body fat in humans.

J. Clin. Endocrinol. Metab. 86(3) , 1144-8, (2001)

The control of body fat is a prominent factor in human health. Animal studies have indicated a homeostatic central nervous system regulation of body fat with particular involvement of the melanocortin...

Adrenalonium chloratum

adrenalon hydrochloride

Adrenone hydrochloride

ADRENALONE,HYDROCHLORIDE

Stryphnonasal

Kephrine hydrochloride

Epinephrine ketone hydrochloride

ADRENALONE HCL

Adrenocorticotropic Hormone (ACTH) (4-10), human