BAY 59-3074

• 常用名: BAY 59-3074
• 英文名: Bay 59-3074
• CAS号: 406205-74-1
• 分子量: 453.35600
• 密度: 1.496g/cm3
• 沸点: 490.569ºC at 760 mmHg
• 分子式: C₁₈H₁₃F₆NO₄S
• 熔点: N/A
• 闪点: 250.488ºC

BAY 59-3074用途

Bay 59-3074是一个新的,有选择性的CB1/CB2 受体的激动剂,Ki值在CB1和CB2中的KI值分别是48.3 nM和45.5 nM。

BAY 59-3074名称

• 中文名: BAY 59-3074
• 英文名: [3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl] 4,4,4-trifluorobutane-1-sulfonate

BAY 59-3074生物活性

• 描述: Bay 59-3074是一个新的,有选择性的CB1/CB2 受体的激动剂,Ki值在CB1和CB2中的KI值分别是48.3 nM和45.5 nM。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 大麻素受体
  研究领域 >> 癌症
• 参考文献:

  [1]. De Vry J et al. 3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl-4,4,4-trifluoro-1-butanesulfonate (BAY 59-3074): a novelcannabinoid Cb1/Cb2 receptor partial agonist with antihyperalgesic and antiallodynic effects. J Pharmacol Exp Ther. 2004 Aug;310(2):620-32

  [2]. De Vry J et al. Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat. Eur J Pharmacol. 2004 Nov 28;505(1-3):127-33.

BAY 59-3074物理化学性质

• 密度: 1.496g/cm3
• 沸点: 490.569ºC at 760 mmHg
• 分子式: C₁₈H₁₃F₆NO₄S
• 分子量: 453.35600
• 闪点: 250.488ºC
• 精确质量: 453.04700
• PSA: 84.77000
• LogP: 6.50128
• InChIKey: LWUSZIVDPJPVBW-UHFFFAOYSA-N
• SMILES: N#Cc1c(Oc2cccc(OS(=O)(=O)CCCC(F)(F)F)c2)cccc1C(F)(F)F
• 折射率: 1.521
• 储存条件: 2-8℃

BAY 59-3074靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Thermal Shift Assay. Domain start/stop: M626-G740 来源：ChEMBL 靶标：Peregrin External Id：CHEMBL4650107

实验名称：Thermal Shift Assay. Domain: start/stop: M1-L298 来源：ChEMBL 靶标：Cyclin-dependent kinase 2 External Id：CHEMBL5062802

实验名称：Selectivity ratio of Ki for rat cannabinoid CB1 receptor to Ki for human cannabinoid ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1838793

实验名称：Displacement of [3H]CP55940 from human cannabinoid CB2 receptor 来源：ChEMBL 靶标：Cannabinoid receptor 2 External Id：CHEMBL1838792

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Rea... 来源：Broad Institute 靶标：histone-lysine N-methyltransferase EZH2 isoform a [Homo sapiens] External Id：2125-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Thermal Shift Assay. Domain: start/stop: P449-E759 来源：ChEMBL 靶标：Fibroblast growth factor receptor 3 External Id：CHEMBL5065466

实验名称：Thermal Shift Assay. Domain: start/stop: M26-R383 来源：ChEMBL 靶标：Glycogen synthase kinase-3 beta External Id：CHEMBL5065589

实验名称：qHTS for Inhibitors of binding or entry into cells for Marburg Virus 来源：NCGC 靶标：gene 4 small orf - Marburg virus External Id：VSVM-OFFLINE

共64条，当前第1页，共7页

1

2

3

4

5

BAY 59-3074英文别名

• bay 59-3074
• hms3269k19
• unii-5fo5z101gu