Echimidine N-oxide

• 常用名: Echimidine N-oxide
• 英文名: Echimidine N-oxide
• CAS号: 41093-89-4
• 分子量: 413.462
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₃₁NO₈
• 熔点: N/A
• 闪点: N/A

Echimidine N-oxide用途

Echimidine N-氧化物是一种吡咯里西啶生物碱,具有乙酰胆碱酯酶(AChE)抑制活性(IC50=0.347 mM)[1]。

Echimidine N-oxide名称

• 英文名: (1R,7aR)-7-[({(2R)-2,3-Dihydroxy-2-[(1S)-1-hydroxyethyl]-3-methylbutanoyl}oxy)methyl]-4-oxido-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl (2Z)-2-methyl-2-butenoate

Echimidine N-oxide生物活性

• 描述: Echimidine N-氧化物是一种吡咯里西啶生物碱,具有乙酰胆碱酯酶(AChE)抑制活性(IC50=0.347 mM)[1]。
• 相关类别:
  研究领域 >> 神经疾病
  信号通路 >> 神经信号通路 >> 疼痛
• 参考文献:

  [1]. Houari Benamar, et al. Acetylcholinesterase inhibitory activity of pyrrolizidine alkaloids from Echium confusum Coincy. Nat Prod Res. 2017 Jun;31(11):1277-1285.

Echimidine N-oxide物理化学性质

• 分子式: C₂₀H₃₁NO₈
• 分子量: 413.462
• 精确质量: 413.204956
• LogP: -0.41
• InChIKey: KDJGEXAPDZNXSD-KCFAIRMISA-N
• SMILES: CC=C(C)C(=O)OC1CC[N+]2([O-])CC=C(COC(=O)C(O)(C(C)O)C(C)(C)O)C12

Echimidine N-oxide靶点实验

查看更多实验

实验名称：Toxicity against Cricetulus griseus CHO (Chinese hamster ovary) cell by MTT assay 来源：ChEMBL 靶标：CHO External Id：CHEMBL3054995

实验名称：Toxicity against Spodoptera frugiperda (fall armyworm) Sf9 cells by MTT assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL3054470

实验名称：Antifeedant activity against Spodoptera littoralis L6 larvae assessed as biomass gain... 来源：ChEMBL 靶标：Spodoptera littoralis External Id：CHEMBL3054471

实验名称：Antifeedant activity against Spodoptera littoralis L6 larvae assessed as food consump... 来源：ChEMBL 靶标：Spodoptera littoralis External Id：CHEMBL3054472

实验名称：Antifeedant activity against Rhopalosiphum padi adults fed on compound treated Hordeu... 来源：ChEMBL 靶标：Rhopalosiphum padi External Id：CHEMBL3054473

实验名称：Antifeedant activity against Myzus persicae (green peach aphid) adults fed on compoun... 来源：ChEMBL 靶标：Myzus persicae External Id：CHEMBL3054474

实验名称：Antifeedant activity against Leptinotarsa decemlineata adults fed on compound treated... 来源：ChEMBL 靶标：Leptinotarsa decemlineata External Id：CHEMBL3054475

实验名称：Antifeedant activity against Spodoptera littoralis sixth-instar larvae fed on compoun... 来源：ChEMBL 靶标：Spodoptera littoralis External Id：CHEMBL3054476

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Echimidine N-oxide英文别名

• (1R,7aR)-7-[({(2R)-2,3-Dihydroxy-2-[(1S)-1-hydroxyethyl]-3-methylbutanoyl}oxy)methyl]-4-oxido-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl (2Z)-2-methyl-2-butenoate