2-苄基-4,5-二氯哒嗪-3-酮

• 常用名: 2-苄基-4,5-二氯哒嗪-3-酮
• 英文名: 2-Benzyl-4,5-dichloropyridazine-3(2H)-one
• CAS号: 41933-33-9
• 分子量: 255.10000
• 密度: 1.38g/cm3
• 沸点: 338ºC at 760 mmHg
• 分子式: C₁₁H₈Cl₂N₂O
• 熔点: 87ºC
• 闪点: 158.2ºC

2-苄基-4,5-二氯哒嗪-3-酮用途

EcDsbB-IN-9(化合物9)是一种有效的大肠杆菌DsbB(EcDsbB)抑制剂,IC50为1.7μM,Ki为46 nM[1]。

2-苄基-4,5-二氯哒嗪-3-酮名称

• 中文名: 4,5-二氯-2-苄基-3(2H)-哒嗪
• 英文名: 2-Benzyl-4,5-dichloropyridazin-3(2H)-one
• 中文别名: 2-苄基-4,5-二氯哒嗪-3(2H)-酮 | 2-苄基-4,5-二氯哒嗪-3-酮 | 2-苄基-4,5-二氯-2,3-二氢吡嗪-3-酮

2-苄基-4,5-二氯哒嗪-3-酮生物活性

• 描述: EcDsbB-IN-9(化合物9)是一种有效的大肠杆菌DsbB(EcDsbB)抑制剂,IC50为1.7μM,Ki为46 nM[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 靶点实验:

  IC50: 1.7 μM (EcDsbB)[1] Ki: 46 nM (EcDsbB)[1]

• 体外研究: EcDsbB-IN-9(化合物9)(0-100μM)导致还原的DsbA(EcDsbB底物)积聚,并以8.5±0.6μM的IC50抑制DsbA的氧化[1]。

2-苄基-4,5-二氯哒嗪-3-酮物理化学性质

• 密度: 1.38g/cm3
• 沸点: 338ºC at 760 mmHg
• 熔点: 87ºC
• 分子式: C₁₁H₈Cl₂N₂O
• 分子量: 255.10000
• 闪点: 158.2ºC
• 精确质量: 254.00100
• PSA: 34.89000
• LogP: 2.59840
• InChIKey: AJHBQZQCDCTOFD-UHFFFAOYSA-N
• SMILES: O=c1c(Cl)c(Cl)cnn1Cc1ccccc1
• 折射率: 1.626
• 储存条件: 室温，干燥

2-苄基-4,5-二氯哒嗪-3-酮MSDS

2-苄基-4,5-二氯哒嗪-3-酮MSDS英文版

2-苄基-4,5-二氯哒嗪-3-酮安全信息

• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S37/39
• 海关编码: 2933990090

2-苄基-4,5-二氯哒嗪-3-酮海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-苄基-4,5-二氯哒嗪-3-酮靶点实验

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2-苄基-4,5-二氯哒嗪-3-酮英文别名

• 2-benzyl-4,5-dichloropyridazin-3-one