CASIN

• 常用名: CASIN
• 英文名: CASIN
• CAS号: 425399-05-9
• 分子量: 306.401
• 密度: 1.2±0.1 g/cm3
• 沸点: 577.8±50.0 °C at 760 mmHg
• 分子式: C₂₀H₂₂N₂O
• 熔点: N/A
• 闪点: 303.3±30.1 °C

CASIN用途

CASIN是一个选择性的GTPase Cdc42抑制剂,IC50值是2 uM。

CASIN名称

• 中文名: CASIN
• 英文名: CASIN

CASIN生物活性

• 描述: CASIN是一个选择性的GTPase Cdc42抑制剂,IC50值是2 uM。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 拉斯
  研究领域 >> 癌症
• 参考文献:

  [1]. Florian MC et al. Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell, 2012 May 4, 10(5):520-30.

  [2]. Peterson JR et al. Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components.

CASIN物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 577.8±50.0 °C at 760 mmHg
• 分子式: C₂₀H₂₂N₂O
• 分子量: 306.401
• 闪点: 303.3±30.1 °C
• 精确质量: 306.173218
• LogP: 3.60
• 外观性状: light yellow solid
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.682
• 储存条件: -20℃

CASIN安全信息

• 危险品运输编码: NONH for all modes of transport

CASIN靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Primary qHTS for Identification of Small Molecule Activators of Huntingtin-Antisense ... 来源：NCGC External Id：huntington-HTTAS8-p1-FF-overN

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_OPM1-m4-1

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CASIN英文别名

• 2-[(6-Phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino]ethanol