3,6-二氨基-9-吖啶酮

• 常用名: 3,6-二氨基-9-吖啶酮
• 英文名: 3,6-Diamino-9(10H)-acridone
• CAS号: 42832-87-1
• 分子量: 225.24600
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₁₁N₃O
• 熔点: >300ºC dec.
• 闪点: N/A

3,6-二氨基-9-吖啶酮用途

3,6-二氨基-9(10H)-吖啶酮是一种拓扑异构酶抑制剂[1]。

3,6-二氨基-9-吖啶酮名称

• 中文名: 3,6-二氨基-9-吖啶酮
• 英文名: 3,6-Diamino-9(10H)-acridone

3,6-二氨基-9-吖啶酮生物活性

• 描述: 3,6-二氨基-9(10H)-吖啶酮是一种拓扑异构酶抑制剂[1]。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> 拓扑异构酶
  研究领域 >> 其他
• 参考文献:

  [1]. Nunhart P, et al. Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity. Bioorg Chem. 2020 Jan;94:103393.

3,6-二氨基-9-吖啶酮物理化学性质

• 熔点: >300ºC dec.
• 分子式: C₁₃H₁₁N₃O
• 分子量: 225.24600
• 精确质量: 225.09000
• PSA: 84.90000
• LogP: 3.00810
• InChIKey: KKKYRANCRKCGDB-UHFFFAOYSA-N
• SMILES: Nc1ccc2c(=O)c3ccc(N)cc3[nH]c2c1

3,6-二氨基-9-吖啶酮安全信息

• 海关编码: 2933990090

3,6-二氨基-9-吖啶酮海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3,6-二氨基-9-吖啶酮靶点实验

查看更多实验

实验名称：Cytotoxic potency required to inhibit L1210 cell growth by 50% after cell drug contac... 来源：ChEMBL 靶标：L1210 External Id：CHEMBL708991

实验名称：Cytotoxic potency required to inhibit SKOV-3 cell growth 50% 来源：ChEMBL 靶标：SK-OV-3 External Id：CHEMBL801182

实验名称：Inhibitory concentration against ethidium:calf thymus DNA (1.26:1) binding at pH 5 来源：ChEMBL 靶标：Calf thymus DNA External Id：CHEMBL654326

实验名称：Cytotoxic potency required to inhibit A2780 cell growth by 50% after cell drug contac... 来源：ChEMBL 靶标：A2780 External Id：CHEMBL619469

实验名称：Inhibitory concentration against ethidium:Calf thymus DNA (1.26:1) binding at pH 7 来源：ChEMBL 靶标：Calf thymus DNA External Id：CHEMBL654328

实验名称：Inhibitory concentration against ethidium:Calf thymus DNA(0.1:1) binding at pH 5 来源：ChEMBL 靶标：Calf thymus DNA External Id：CHEMBL651390

实验名称：Cytotoxic potency required to inhibit CH1 cell growth by 50% 来源：ChEMBL 靶标：CH1 External Id：CHEMBL657466

实验名称：Concentration required to give 50% fluorescence quenching of bound ethidium for [ethi... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL663967

实验名称：Concentration required to give 50% fluorescence quenching of bound ethidium for [ethi... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL663968

共9条，当前第1页，共1页

1

3,6-二氨基-9-吖啶酮英文别名

• 3,6-diamino-10H-acridin-9-one