OGT-IN-2

• 常用名: OGT-IN-2
• 英文名: ST 045849
• CAS号: 442665-87-4
• 分子量: 446.99
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₇ClN₂O₃S
• 熔点: N/A
• 闪点: N/A

OGT-IN-2用途

OGT-IN-2是一种O-GlcNAc转移酶(OGT)抑制剂,IC50为53μM。OGT-IN-2耗尽细胞内丙氨酸,减少癌细胞对葡萄糖的消耗。OGT-IN-2降低妊娠期糖尿病小鼠内质网应激和凋亡标记物,减少糖尿病小鼠胚胎神经管缺陷。

OGT-IN-2名称

• 英文名: OGT-IN-2

OGT-IN-2生物活性

• 描述: OGT-IN-2是一种O-GlcNAc转移酶(OGT)抑制剂,IC50为53μM。OGT-IN-2耗尽细胞内丙氨酸,减少癌细胞对葡萄糖的消耗。OGT-IN-2降低妊娠期糖尿病小鼠内质网应激和凋亡标记物,减少糖尿病小鼠胚胎神经管缺陷。
• 相关类别:
  信号通路 >> 其他 >> 其他

OGT-IN-2物理化学性质

• 分子式: C₂₃H₂₇ClN₂O₃S
• 分子量: 446.99
• InChIKey: HLPZEZRNGAXCJH-UHFFFAOYSA-N
• SMILES: O=C(O)C1CC(=O)N(CCC23CC4CC(CC(C4)C2)C3)C(=Nc2ccc(Cl)cc2)S1
• 储存条件: 2-8°C，干燥，密封

OGT-IN-2安全信息

• 危害码 (欧洲): Xi

OGT-IN-2靶点实验

查看更多实验

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：A screen for compounds that inhibit viral RNA polymerase binding and polymerization a... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Chain A, Poliovirus Polymerase With Gtp External Id：HMS750

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