ST 045849
Modify Date: 2025-08-25 17:30:11
ST 045849 structure
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Common Name | ST 045849 | ||
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| CAS Number | 442665-87-4 | Molecular Weight | 446.99 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H27ClN2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ST 045849OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice. |
| Name | OGT-IN-2 |
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| Description | OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice. |
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| Related Catalog |
| Molecular Formula | C23H27ClN2O3S |
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| Molecular Weight | 446.99 |
| InChIKey | HLPZEZRNGAXCJH-UHFFFAOYSA-N |
| SMILES | O=C(O)C1CC(=O)N(CCC23CC4CC(CC(C4)C2)C3)C(=Nc2ccc(Cl)cc2)S1 |
| Hazard Codes | Xi |
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