路路通酸

• 常用名: 路路通酸
• 英文名: Betulonic acid
• CAS号: 4481-62-3
• 分子量: 454.684
• 密度: 1.1±0.1 g/cm3
• 沸点: 548.1±33.0 °C at 760 mmHg
• 分子式: C₃₀H₄₆O₃
• 熔点: 264 °C
• 闪点: 299.4±21.9 °C

路路通酸用途

Betulonic acid属于五环三萜衍生物类,有抗肿瘤的性质。

路路通酸名称

• 中文名: 路路通酸
• 英文名: Betulonicacid
• 中文别名: 桦木酮酸 | 桦木酮酸,白桦脂酸,白桦脂酮酸 | 白桦脂酮酸

路路通酸生物活性

• 描述: Betulonic acid属于五环三萜衍生物类,有抗肿瘤的性质。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他
  天然产物 >> 萜类化合物和糖苷
• 参考文献:

  [1]. Zhang J et al. Employing rubusoside to improve the solubility and permeability of antitumor compound betulonic acid. Nanomedicine (Lond). 2016 Oct 19.

  [2]. Semenov DE et al. Hepatoprotective properties of betulonic acid amide and heptral in toxic liver injury induced by carbon tetrachloride in combination with ethanol.Bull Exp Biol Med. 2015 Jan;158(3):336-41.

路路通酸物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 548.1±33.0 °C at 760 mmHg
• 熔点: 264 °C
• 分子式: C₃₀H₄₆O₃
• 分子量: 454.684
• 闪点: 299.4±21.9 °C
• 精确质量: 454.344696
• PSA: 54.37000
• LogP: 8.36
• InChIKey: SLJTWDNVZKIDAU-SVAFSPIFSA-N
• SMILES: C=C(C)C1CCC2(C(=O)O)CCC3(C)C(CCC4C5(C)CCC(=O)C(C)(C)C5CCC43C)C12
• 外观性状: 固体;White to Almost white powder to crystal
• 蒸汽压: 0.0±3.2 mmHg at 25°C
• 折射率: 1.527
• 储存条件: 0-10°C;避免加热

路路通酸安全信息

• 危害码 (欧洲): Xi
• 安全声明 (欧洲): 24/25

路路通酸靶点实验

查看更多实验

实验名称：Antiproliferative activity in human HeLa cells by sulforhodamine B assay 来源：ChEMBL 靶标：HeLa External Id：CHEMBL4135984

实验名称：Antiproliferative activity in human SiHa cells by sulforhodamine B assay 来源：ChEMBL 靶标：SiHa External Id：CHEMBL4135985

实验名称：Endothelial cell specificity of compound was determined as cytotoxicity on human tumo... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL845415

实验名称：Endothelial cell specificity of compound was determined as cytotoxicity on human tumo... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL845414

实验名称：Endothelial cell specificity of compound was determined as cytotoxicity on human tumo... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL845413

实验名称：Endothelial cell specificity of compound was determined as cytotoxicity on human tumo... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL845412

实验名称：Inhibition of Clostridium BoNT/A protease light chain 来源：ChEMBL 靶标：Botulinum neurotoxin type A External Id：CHEMBL1764191

实验名称：Cytotoxic activity in human HeLa cells by sulforhodamine B assay 来源：ChEMBL 靶标：HeLa External Id：CHEMBL4135961

实验名称：Cytotoxic activity in African green monkey Vero cells by sulforhodamine B assay 来源：ChEMBL 靶标：Vero External Id：CHEMBL4135968

实验名称：Cytotoxic activity in HEK293 cells by sulforhodamine B assay 来源：ChEMBL 靶标：HEK293 External Id：CHEMBL4135969

共194条，当前第1页，共20页

1

2

3

4

5

路路通酸英文别名

• Betulinonic acid
• 3-Oxolup-20(29)-en-28-oic acid
• Liquidambaricacid
• Betulonic acid
• LiquidaMba