AChE-IN-17

• 常用名: AChE-IN-17
• 英文名: AChE-IN-17
• CAS号: 460345-17-9
• 分子量: 424.49
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₈O₆
• 熔点: N/A
• 闪点: N/A

AChE-IN-17用途

AChE-IN-17(化合物1)是一种有效的AChE抑制剂,其IC50值为28.98μM。AChE-IN-17可显著防止H2O2诱导的PC12细胞死亡,具有良好的神经保护作用。AChE-IN-17可用于研究神经退行性疾病(NDs)[1]。

AChE-IN-17名称

• 英文名: AChE-IN-17

AChE-IN-17生物活性

• 描述: AChE-IN-17(化合物1)是一种有效的AChE抑制剂,其IC50值为28.98μM。AChE-IN-17可显著防止H2O2诱导的PC12细胞死亡,具有良好的神经保护作用。AChE-IN-17可用于研究神经退行性疾病(NDs)[1]。
• 相关类别:
  研究领域 >> 神经疾病
  信号通路 >> 神经信号通路 >> 疼痛
• 靶点实验:

  IC50: 28.98 μM (AChE)[1]

• 参考文献:

  [1]. Santi MD, et al. Neuroprotective effects of prenylated flavanones isolated from Dalea species, in vitro and in silico studies. Eur J Med Chem. 2020;206:112718.

AChE-IN-17物理化学性质

• 分子式: C₂₅H₂₈O₆
• 分子量: 424.49
• InChIKey: PCNCQAWYRGWMFH-QFIPXVFZSA-N
• SMILES: C=CC(C)(C)c1cc(C2CC(=O)c3c(O)cc(O)c(CC=C(C)C)c3O2)c(O)cc1O

AChE-IN-17靶点实验

查看更多实验

实验名称：Anthelmintic activity against Ancylostoma ceylanicum isolated from infected Syrian ha... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3867997

实验名称：Anthelmintic activity against Ancylostoma ceylanicum isolated from infected Syrian ha... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3867998

实验名称：Neuroprotective activity against H2O2-induced cell death in human PC12D cells at 0.5 ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4774392

实验名称：Anthelmintic activity against Ancylostoma ceylanicum isolated from infected Syrian ha... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3867999

实验名称：Anthelmintic activity against Ancylostoma ceylanicum isolated from infected Syrian ha... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3868000

实验名称：Anthelmintic activity against Ancylostoma ceylanicum isolated from infected Syrian ha... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3868001

实验名称：Effect on Syrian hamster splenocytes proliferation assessed as stimulation index by B... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3868002

实验名称：Antimicrobial activity against Staphylococcus aureus after 18 hrs by serial twofold d... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1027621

实验名称：Neuroprotective activity against H2O2-induced neuronal death in Sprague-Dawley rat pr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4774386

实验名称：Neuroprotective activity against H2O2-induced neuronal death in Sprague-Dawley rat pr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4774387

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