3,5-DIHYDROXY-7-METHOXYFLAVONE

• 常用名: 3,5-DIHYDROXY-7-METHOXYFLAVONE
• 英文名: 3,5-DIHYDROXY-7-METHOXYFLAVONE
• CAS号: 480-14-8
• 分子量: 284.26
• 密度: 1.445g/cm3
• 沸点: 512.9ºC at 760 mmHg
• 分子式: C₁₆H₁₂O₅
• 熔点: N/A
• 闪点: 195.9ºC

3,5-DIHYDROXY-7-METHOXYFLAVONE用途

依扎品碱是一种对癌症细胞株具有细胞毒性作用的二氢查尔酮。伊扎尔皮宁可从卡氏芒廷菊的叶片中分离得到[1]。

3,5-DIHYDROXY-7-METHOXYFLAVONE名称

• 英文名: 3,5-dihydroxy-7-methoxy-2-phenylchromen-4-one

3,5-DIHYDROXY-7-METHOXYFLAVONE生物活性

• 描述: 依扎品碱是一种对癌症细胞株具有细胞毒性作用的二氢查尔酮。伊扎尔皮宁可从卡氏芒廷菊的叶片中分离得到[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体外研究: 伊扎尔皮宁(化合物9)抑制癌细胞系的细胞活力,IC50分别为 8.9μg/mL(P388)和 15.0μg/mL(HT-29)[1]
• 参考文献:

  [1]. Chen JJ, et al. Cytotoxic chalcones and flavonoids from the leaves of Muntingia calabura. Planta Med. 2005 Oct;71(10):970-3.

3,5-DIHYDROXY-7-METHOXYFLAVONE物理化学性质

• 密度: 1.445g/cm3
• 沸点: 512.9ºC at 760 mmHg
• 分子式: C₁₆H₁₂O₅
• 分子量: 284.26
• 闪点: 195.9ºC
• 精确质量: 284.06800
• PSA: 79.90000
• LogP: 2.87980
• InChIKey: PVJNLMXWZXXHSZ-UHFFFAOYSA-N
• SMILES: COc1cc(O)c2c(=O)c(O)c(-c3ccccc3)oc2c1
• 蒸汽压: 2.41E-11mmHg at 25°C
• 折射率: 1.68

3,5-DIHYDROXY-7-METHOXYFLAVONE靶点实验

查看更多实验

实验名称：Cytotoxicity against human KB cells at 20 uM after 72 hrs by neutral red staining 来源：ChEMBL 靶标：KB External Id：CHEMBL2168276

实验名称：Inhibition of rat RBL2H3 cell degranulation assessed as inhibition of beta-hexosamida... 来源：ChEMBL 靶标：RBL-2H3 External Id：CHEMBL940524

实验名称：Inhibition of LPS-induced NO production in ddY mouse macrophages assessed as nitrate ... 来源：ChEMBL 靶标：Macrophage External Id：CHEMBL942481

实验名称：Inhibition of rat RBL2H3 cell degranulation assessed as inhibition of beta-hexosamida... 来源：ChEMBL 靶标：RBL-2H3 External Id：CHEMBL940523

实验名称：Inhibition of LPS-induced NO production in ddY mouse macrophages assessed as nitrate ... 来源：ChEMBL 靶标：Macrophage External Id：CHEMBL942480

实验名称：Inhibition of LPS-induced NO production in ddY mouse macrophages assessed as nitrate ... 来源：ChEMBL 靶标：Macrophage External Id：CHEMBL942482

实验名称：Inhibition of rat RBL2H3 cell degranulation assessed as inhibition of beta-hexosamida... 来源：ChEMBL 靶标：RBL-2H3 External Id：CHEMBL940522

实验名称：Inhibition of LPS-induced NO production in ddY mouse macrophages assessed as nitrate ... 来源：ChEMBL 靶标：Macrophage External Id：CHEMBL942479

实验名称：Cytotoxicity against ddY mouse macrophages after 20 hrs by MTT assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL940521

实验名称：Inhibition of LPS-induced NO production in ddY mouse macrophages assessed as nitrate ... 来源：ChEMBL 靶标：Macrophage External Id：CHEMBL942478

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3,5-DIHYDROXY-7-METHOXYFLAVONE英文别名

• 7-O-Methylgalangin
• galangin 3-methyl ether
• 3,5-dihydroxy-7-methoxyflavone
• Isalpinin
• Izalpinin
• 3,5-dihydroxy-7-methoxy-2-phenyl-chromen-4-one
• galangin-7-methyl ether