异刺芒柄花素

• 常用名: 异刺芒柄花素
• 英文名: Isoformononetin
• CAS号: 486-63-5
• 分子量: 268.26400
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₂O₄
• 熔点: N/A
• 闪点: N/A

异刺芒柄花素用途

Isoformononetin 是一种类似于大豆苷元 (HY-N0019) 的物质,具有免疫保护作用。Isoformononetin 在雌激素缺乏骨丢失条件下抑制 Th17 细胞和 b 淋巴细胞分化促进成骨。

异刺芒柄花素名称

• 中文名: 3-(4-羟基苯基)-7-甲氧基-4H-色烯-4-酮
• 英文名: isoformononetin

异刺芒柄花素生物活性

• 描述: Isoformononetin 是一种类似于大豆苷元 (HY-N0019) 的物质,具有免疫保护作用。Isoformononetin 在雌激素缺乏骨丢失条件下抑制 Th17 细胞和 b 淋巴细胞分化促进成骨。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Mohd N Mansoori, et al. Methoxyisoflavones Formononetin and Isoformononetin Inhibit the Differentiation of Th17 Cells and B-cell Lymphopoesis to Promote Osteogenesis in Estrogen-Deficient Bone Loss Conditions. Menopause

异刺芒柄花素物理化学性质

• 分子式: C₁₆H₁₂O₄
• 分子量: 268.26400
• 精确质量: 268.07400
• PSA: 59.67000
• LogP: 3.17420
• InChIKey: LNIQZRIHAMVRJA-UHFFFAOYSA-N
• SMILES: COc1ccc2c(=O)c(-c3ccc(O)cc3)coc2c1

异刺芒柄花素安全信息

• 海关编码: 2914509090

异刺芒柄花素海关

• 海关编码: 2914509090
• 中文概述: 2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途, 丙酮报明包装
• Summary: HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

异刺芒柄花素靶点实验

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实验名称：Inhibition of XOD (unknown origin) using xanthine as substrate at 1 uM preincubated f... 来源：ChEMBL 靶标：Xanthine dehydrogenase/oxidase External Id：CHEMBL5372172

实验名称：Inhibition of XOD (unknown origin) using xanthine as substrate preincubated for 30 mi... 来源：ChEMBL 靶标：Xanthine dehydrogenase/oxidase External Id：CHEMBL5372173

实验名称：Displacement of fluorescent labeled ES2 from recombinant ERalpha at 10 uM relative to... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL1219561

实验名称：Displacement of fluorescent labeled ES2 from recombinant ERalpha relative to estradio... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL1219559

实验名称：Induction of mineralization in Sprague-Dawley rat calvaria derived primary osteoblast... 来源：ChEMBL 靶标：Osteoblast External Id：CHEMBL1023758

实验名称：Antiestrogenic activity at ER in human MCF7 cells assessed as inhibition of estradiol... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL1219558

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre... 来源：11924 靶标：N/A External Id：CGM data for Cell Systems paper Dec 2015

实验名称：Estrogenic activity at ER in human MCF7 cells assessed as increase of estradiol-induc... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL1219555

实验名称：Estrogenic activity in human MCF7 cells assessed as increase of ER-mediated PR expres... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL1219569

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异刺芒柄花素英文别名

• 7-O-methyldaidzein
• HMO
• ISOFORMONENTIN
• 3-(4-hydroxyphenyl)-7-methoxychromen-4-one
• 4'-HYDROXY-7-METHOXYISOFLAVONE