Isoformononetin

Modify Date: 2025-08-27 17:28:38

Isoformononetin Structure
Isoformononetin structure
Common Name Isoformononetin
CAS Number 486-63-5 Molecular Weight 268.26400
Density N/A Boiling Point N/A
Molecular Formula C16H12O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Isoformononetin


Isoformononetin is an analog of Daidzein (HY-N0019) and has immunoprotective effects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions[1].

 Names

Name isoformononetin
Synonym More Synonyms

 Isoformononetin Biological Activity

Description Isoformononetin is an analog of Daidzein (HY-N0019) and has immunoprotective effects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions[1].
Related Catalog
References

[1]. Mohd N Mansoori, et al. Methoxyisoflavones Formononetin and Isoformononetin Inhibit the Differentiation of Th17 Cells and B-cell Lymphopoesis to Promote Osteogenesis in Estrogen-Deficient Bone Loss Conditions. Menopause

 Chemical & Physical Properties

Molecular Formula C16H12O4
Molecular Weight 268.26400
Exact Mass 268.07400
PSA 59.67000
LogP 3.17420
InChIKey LNIQZRIHAMVRJA-UHFFFAOYSA-N
SMILES COc1ccc2c(=O)c(-c3ccc(O)cc3)coc2c1

 Safety Information

HS Code 2914509090

 Precursor & DownStream

Precursor  0

DownStream  2

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 IsoformononetinBioassay

View more

Name: Inhibition of XOD (unknown origin) using xanthine as substrate at 1 uM preincubated f...
Source: ChEMBL
Target: Xanthine dehydrogenase/oxidase
External Id: CHEMBL5372172
Name: Inhibition of XOD (unknown origin) using xanthine as substrate preincubated for 30 mi...
Source: ChEMBL
Target: Xanthine dehydrogenase/oxidase
External Id: CHEMBL5372173
Name: Displacement of fluorescent labeled ES2 from recombinant ERalpha at 10 uM relative to...
Source: ChEMBL
Target: Estrogen receptor
External Id: CHEMBL1219561
Name: Displacement of fluorescent labeled ES2 from recombinant ERalpha relative to estradio...
Source: ChEMBL
Target: Estrogen receptor
External Id: CHEMBL1219559
Name: Induction of mineralization in Sprague-Dawley rat calvaria derived primary osteoblast...
Source: ChEMBL
Target: Osteoblast
External Id: CHEMBL1023758
Name: Antiestrogenic activity at ER in human MCF7 cells assessed as inhibition of estradiol...
Source: ChEMBL
Target: Estrogen receptor
External Id: CHEMBL1219558
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre...
Source: 11924
Target: N/A
External Id: CGM data for Cell Systems paper Dec 2015
Name: Estrogenic activity at ER in human MCF7 cells assessed as increase of estradiol-induc...
Source: ChEMBL
Target: Estrogen receptor
External Id: CHEMBL1219555
Name: Estrogenic activity in human MCF7 cells assessed as increase of ER-mediated PR expres...
Source: ChEMBL
Target: MCF7
External Id: CHEMBL1219569
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 Synonyms

7-O-methyldaidzein
HMO
ISOFORMONENTIN
3-(4-hydroxyphenyl)-7-methoxychromen-4-one
4'-HYDROXY-7-METHOXYISOFLAVONE
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