α-Truxillic acid

• 常用名: α-Truxillic acid
• 英文名: 2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid
• CAS号: 490-20-0
• 分子量: 296.317
• 密度: 1.3±0.1 g/cm3
• 沸点: 470.5±45.0 °C at 760 mmHg
• 分子式: C₁₈H₁₆O₄
• 熔点: N/A
• 闪点: 252.4±25.2 °C

α-Truxillic acid用途

α-Truxillic acid 是由两个 α-trans-cinnamic acid 分子构成的二聚体,具有抗炎活性。

α-Truxillic acid名称

• 英文名: 2,4-diphenylcyclobutane-1,3-dicarboxylic acid

α-Truxillic acid生物活性

• 描述: α-Truxillic acid 是由两个 α-trans-cinnamic acid 分子构成的二聚体,具有抗炎活性。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Chi YM, et al. Antinociceptive activities of alpha-truxillic acid and beta-truxinic acid derivatives. Biol Pharm Bull. 2006 Mar;29(3):580-4.

α-Truxillic acid物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 470.5±45.0 °C at 760 mmHg
• 分子式: C₁₈H₁₆O₄
• 分子量: 296.317
• 闪点: 252.4±25.2 °C
• 精确质量: 296.104858
• PSA: 74.60000
• LogP: 3.57
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.629

α-Truxillic acid靶点实验

查看更多实验

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：A screen for compounds that inhibit viral RNA polymerase binding and polymerization a... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Chain A, Poliovirus Polymerase With Gtp External Id：HMS750

实验名称：Antinociceptive activity in C57BL/6 mouse model of complete Freund's adjuvant-induced... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4271809

实验名称：Displacement of DAUDA from recombinant human N-terminal His-tagged FABP3 expressed in... 来源：ChEMBL 靶标：Fatty acid-binding protein, heart External Id：CHEMBL4271806

实验名称：qHTS assay for inhibitors of human lactate dehydrogenase 来源：NCGC 靶标：N/A External Id：LDHA

实验名称：Displacement of ANS from recombinant human N-terminal His-tagged FABP7 expressed in E... 来源：ChEMBL 靶标：Fatty acid-binding protein, brain External Id：CHEMBL4271808

实验名称：Dicer-mediated maturation of pre-microRNA 来源：Center for Chemical Genomics, University of Michigan 靶标：N/A External Id：TargetID_659_CEMA

实验名称：Displacement of DAUDA from recombinant human N-terminal His-tagged FABP5 expressed in... 来源：ChEMBL 靶标：Fatty acid-binding protein 5 External Id：CHEMBL4271807

实验名称：Inhibitors of CDC25B-CDK2/CyclinA interaction 来源：Center for Chemical Genomics, University of Michigan External Id：MScreen:TargetID_600

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α-Truxillic acid英文别名

• truxillic acid
• 2c,4t-Diphenyl-cyclobutan-1r,3t-dicarbonsaeure
• 2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid
• 2,4-diphenyl-cyclobutane-1,3-dicarboxylic acid
• 2,4-diphenylcyclobutane-1,3-dicarboxylic acid