碘依可酯

• 常用名: 碘依可酯
• 英文名: Echothiophate Iodide
• CAS号: 513-10-0
• 分子量: 383.22700
• 密度: N/A
• 沸点: N/A
• 分子式: C₉H₂₃INO₃PS
• 熔点: N/A
• 闪点: N/A

碘依可酯用途

碘硫氰酸酯是一种有效的hBChE(人类丁酰胆碱酯酶)抑制剂。碘化硫代硫酸酯是一种长效抗胆碱酯酶剂。碘碘酸异硫酯可用于青光眼研究[1][2]。

碘依可酯名称

• 中文名: 碘依可酯
• 英文名: ecothiopate iodide

碘依可酯生物活性

• 描述: 碘硫氰酸酯是一种有效的hBChE(人类丁酰胆碱酯酶)抑制剂。碘化硫代硫酸酯是一种长效抗胆碱酯酶剂。碘碘酸异硫酯可用于青光眼研究[1][2]。
• 相关类别:
  研究领域 >> 神经疾病
  信号通路 >> 神经信号通路 >> 疼痛
• 靶点实验:

  Butyrylcholinesterase

• 参考文献:

  [1]. Nachon F, et al. Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging. Biochemistry. 2005 Feb 1;44(4):1154-62.

  [2]. HUMPHREYS JA, et al. Systemic effects produced by echothiophate iodide in treatment of glaucoma. Arch Ophthalmol. 1963 Jun;69:737-43.

碘依可酯物理化学性质

• 分子式: C₉H₂₃INO₃PS
• 分子量: 383.22700
• 精确质量: 383.01800
• PSA: 70.64000
• InChIKey: OVXQHPWHMXOFRD-UHFFFAOYSA-M
• SMILES: CCOP(=O)(OCC)SCC[N+](C)(C)C.[I-]

碘依可酯毒性和生态

碘依可酯安全信息

• 危险品运输编码: UN 3249
• 包装等级: II
• 危险类别: 6.1(a)
• 海关编码: 2931900090

碘依可酯海关

• 海关编码: 2931900090
• 中文概述: 2931900090. 其他有机-无机化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:6.5%. 普通关税:30.0%
• Summary: 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

碘依可酯靶点实验

查看更多实验

实验名称：Induction of electric eel AChE phosphorylation 来源：ChEMBL 靶标：Acetylcholinesterase External Id：CHEMBL3285170

实验名称：Binding affinity to electric eel AChE 来源：ChEMBL 靶标：Acetylcholinesterase External Id：CHEMBL3285169

实验名称：Acute toxicity in sc dosed Ness-Ziona mouse assessed as mortality after 24 hrs 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3285172

实验名称：Inhibition of electric eel AChE assessed as decrease in thiophenol formation using ac... 来源：ChEMBL 靶标：Acetylcholinesterase External Id：CHEMBL3285171

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碘依可酯英文别名

• Ecothiopati iodidum
• Echodide
• 2-(diethoxyphosphinyl)thio-N,N,N-trimethylethanaminium iodide
• diethoxyphosphinylthiocholine iodide
• Ecothiophate iodide
• Echothiophate iodide
• Ioduro de ecotiopato
• 2-diethoxyphosphorylsulfanylethyl(trimethyl)azanium,iodide
• ecothiopate
• Ecostigmini jodidum
• UNII-BA9QH3P00T
• Iodure d'ecothiopate
• Phospholine iodide